Tissue mechanics regulate brain development, homeostasis and disease

JM Barnes, L Przybyla, VM Weaver - Journal of cell science, 2017 - journals.biologists.com
All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Diffusion-weighted imaging in cancer: physical foundations and applications of restriction spectrum imaging

NS White, CR McDonald, N Farid, J Kuperman… - Cancer research, 2014 - AACR
Diffusion-weighted imaging (DWI) has been at the forefront of cancer imaging since the early
2000s. Before its application in clinical oncology, this powerful technique had already …

Radiogenomics of glioblastoma: machine learning–based classification of molecular characteristics by using multiparametric and multiregional MR imaging features

P Kickingereder, D Bonekamp, M Nowosielski, A Kratz… - Radiology, 2016 - pubs.rsna.org
Purpose To evaluate the association of multiparametric and multiregional magnetic
resonance (MR) imaging features with key molecular characteristics in patients with newly …

Radiomics for precision medicine in glioblastoma

K Aftab, FB Aamir, S Mallick, F Mubarak… - Journal of neuro …, 2022 - Springer
Introduction Being the most common primary brain tumor, glioblastoma presents as an
extremely challenging malignancy to treat with dismal outcomes despite treatment. Varying …

ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI

ER Gerstner, Z Zhang, JR Fink, M Muzi, L Hanna… - Clinical Cancer …, 2016 - AACR
Purpose: Structural and functional alterations in tumor vasculature are thought to contribute
to tumor hypoxia which is a primary driver of malignancy through its negative impact on the …

Radiogenomics and imaging phenotypes in glioblastoma: novel observations and correlation with molecular characteristics

BM Ellingson - Current neurology and neuroscience reports, 2015 - Springer
Radiogenomics is a provocative new area of research based on decades of previous work
examining the association between radiological and histological features. Many generalized …

COL11A1/(pro)collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression

F Vázquez-Villa, M García-Ocaña, JA Galván… - Tumor Biology, 2015 - Springer
The COL11A1 human gene codes for the α1 chain of procollagen 11A1 and mature
collagen 11A1, an extracellular minor fibrillar collagen. Under regular conditions, this gene …

[HTML][HTML] Radiomics prognostication model in glioblastoma using diffusion-and perfusion-weighted MRI

JE Park, HS Kim, Y Jo, RE Yoo, SH Choi, SJ Nam… - Scientific reports, 2020 - nature.com
We aimed to develop and validate a multiparametric MR radiomics model using
conventional, diffusion-, and perfusion-weighted MR imaging for better prognostication in …

Consideration of the Mechanical Properties of Hydrogels for Brain Tissue Engineering and Brain-on-a-chip

HN Kim, N Choi - BioChip Journal, 2019 - Springer
To present a more physiologically relevant microenvironment for cells, hydrogel-based
threedimensional culture platforms have been widely adopted. As noted by multiple …

[HTML][HTML] Emerging biomarkers in glioblastoma

MG McNamara, S Sahebjam, WP Mason - Cancers, 2013 - mdpi.com
Glioblastoma, the most common primary brain tumor, has few available therapies providing
significant improvement in survival. Molecular signatures associated with tumor …