High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis

H Meng, VM Tutino, J Xiang… - American Journal of …, 2014 - Am Soc Neuroradiology
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …

What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review

KM Saqr, S Rashad, S Tupin… - Journal of Cerebral …, 2020 - journals.sagepub.com
Despite the plethora of published studies on intracranial aneurysms (IAs) hemodynamic
using computational fluid dynamics (CFD), limited progress has been made towards …

Flow conditions in the intracranial aneurysm lumen are associated with inflammation and degenerative changes of the aneurysm wall

J Cebral, E Ollikainen, BJ Chung… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …

CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment

J Xiang, VM Tutino, KV Snyder… - American Journal of …, 2014 - Am Soc Neuroradiology
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …

[HTML][HTML] Real-world variability in the prediction of intracranial aneurysm wall shear stress: the 2015 international aneurysm CFD challenge

K Valen-Sendstad, AW Bergersen… - Cardiovascular …, 2018 - Springer
Purpose Image-based computational fluid dynamics (CFD) is widely used to predict
intracranial aneurysm wall shear stress (WSS), particularly with the goal of improving rupture …

Mind the gap: impact of computational fluid dynamics solution strategy on prediction of intracranial aneurysm hemodynamics and rupture status indicators

K Valen-Sendstad… - American Journal of …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Computational fluid dynamics has become a popular tool
for studying intracranial aneurysm hemodynamics, demonstrating success for retrospectively …

CFD for evaluation and treatment planning of aneurysms: review of proposed clinical uses and their challenges

B Chung, JR Cebral - Annals of biomedical engineering, 2015 - Springer
Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …

[HTML][HTML] Reinforcement learning for patient-specific optimal stenting of intracranial aneurysms

E Hachem, P Meliga, A Goetz, PJ Rico, J Viquerat… - Scientific Reports, 2023 - nature.com
Developing new capabilities to predict the risk of intracranial aneurysm rupture and to
improve treatment outcomes in the follow-up of endovascular repair is of tremendous …

A comparison of 4D flow MRI-derived wall shear stress with computational fluid dynamics methods for intracranial aneurysms and carotid bifurcations—a review

J Szajer, K Ho-Shon - Magnetic resonance imaging, 2018 - Elsevier
Background 4D flow MRI is a relatively quick method for obtaining wall shear stress (WSS)
in vivo, a hemodynamic parameter which has shown promise in risk stratification for rupture …

Suggested connections between risk factors of intracranial aneurysms: a review

JR Cebral, M Raschi - Annals of biomedical engineering, 2013 - Springer
The purpose of this article is to review studies of aneurysm risk factors and the suggested
hypotheses that connect the different risk factors and the underlying mechanisms governing …