Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its
association with an aggressive tumour phenotype and therapeutic resistance. Given its …

Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Hypoxia is a pathological condition arising in living tissues when oxygen supply does not
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …

Purpose Hypoxia is a condition of insufficient oxygen to support metabolism which occurs
when the vascular supply is interrupted, or when a tumour outgrows its vascular supply. It is …

Copper homeostasis is tightly regulated in both prokaryotic and eukaryotic cells to ensure
sufficient amounts for cuproprotein biosynthesis, while limiting oxidative stress production …

The hypoxic state in a solid tumor refers to the internal hypoxic environment that appears as
the tumor volume increases (the maximum radius exceeds 180-200 microns). This state can …

Simple Summary Conventional magnetic resonance imaging (MRI) sequences have known
limitations in target delineation for radiation treatment (RT) planning of cerebral gliomas …

Background Tumor hypoxia (low tissue oxygenation) is an adverse condition of the solid
tumor environment, associated with malignant progression, radiotherapy resistance, and …

The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

Targeted molecular imaging with positron emission tomography (PET) constitutes a
successful technique for detecting and diagnosing disease conditions promptly and …