In vivo cerebral aneurysm models

JW Thompson, O Elwardany, DJ McCarthy… - Neurosurgical …, 2019 - thejns.org
Cerebral aneurysm rupture is a devastating event resulting in subarachnoid hemorrhage
and is associated with significant morbidity and death. Up to 50% of individuals do not …

Recurrence of endovascularly and microsurgically treated intracranial aneurysms—review of the putative role of aneurysm wall biology

S Marbacher, M Niemelä, J Hernesniemi, J Frösén - Neurosurgical review, 2019 - Springer
Although endovascular therapy has been proven safe and has become in many centers the
primary method of treatment for intracranial aneurysms, the long-term durability of …

Flow diversion in middle cerebral artery aneurysms: is it really an all-purpose treatment?

OM Topcuoglu, E Akgul, E Daglioglu, ED Topcuoglu… - World neurosurgery, 2016 - Elsevier
Background and Objective The outcome of flow diversion for middle cerebral artery (MCA)
aneurysms, one of the most common sites for intracranial aneurysms, has not been defined …

[HTML][HTML] Saccular aneurysm models featuring growth and rupture: a systematic review

S Marbacher, S Wanderer, F Strange, BE Grüter… - Brain sciences, 2020 - mdpi.com
Background. Most available large animal extracranial aneurysm models feature healthy non-
degenerated aneurysm pouches with stable long-term follow-ups and extensive healing …

Testing flow diversion in animal models: a systematic review

R Fahed, J Raymond, C Ducroux, JC Gentric… - Neuroradiology, 2016 - Springer
Introduction Flow diversion (FD) is increasingly used to treat intracranial aneurysms. We
sought to systematically review published studies to assess the quality of reporting and …

Intraluminal cell transplantation prevents growth and rupture in a model of rupture-prone saccular aneurysms

S Marbacher, J Frösén, J Marjamaa, A Anisimov… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Aneurysm occlusion by intraluminal thrombus formation is the
desired effect of all endovascular treatments. Intraluminal thrombus may, however …

[HTML][HTML] Usefulness of the pipeline embolic device for large and giant carotid cavernous aneurysms

S Miyachi, R Hiramatsu, H Ohnishi, R Yagi… - …, 2017 - ncbi.nlm.nih.gov
Purpose Conventional coil embolization for large carotid cavernous aneurysms (CCAs) has
limited utility due to its inability to prevent recurrences and reduce mass effect. Trapping of …

Bypass surgeries in the treatment of cerebral aneurysms

T Hara, S Arai, Y Goto, T Takizawa, T Uchida - Trends in Cerebrovascular …, 2016 - Springer
Background During surgery for cerebral aneurysm, revascularization techniques are
occasionally needed to (1) treat an aneurysm (trapping or flow alteration);(2) preserve blood …

Activated platelet-homing nanoplatform for targeting magnetic resonance imaging of aneurysm-related thrombus in rabbits

Y Zhang, S Cheng, Y He, C Tang, F Liu… - … Applied Materials & …, 2021 - ACS Publications
Thrombosis is closely related to the instability of intracranial aneurysm (IA), whose rupture is
associated with high morbidity and mortality. It is difficult to detect an IA-related thrombus …

[HTML][HTML] Imaging of intracranial aneurysms in animals: a systematic review of modalities

AF Cayron, S Morel, E Allémann, P Bijlenga… - Neurosurgical …, 2023 - Springer
Intracranial aneurysm (IA) animal models are paramount to study IA pathophysiology and to
test new endovascular treatments. A number of in vivo imaging modalities are available to …