The biophysical role of hemodynamics in the pathogenesis of cerebral aneurysm formation and rupture

S Soldozy, P Norat, M Elsarrag, A Chatrath… - Neurosurgical …, 2019 - thejns.org
The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …

ACR appropriateness criteria® cerebrovascular disease

MB Salmela, S Mortazavi, BD Jagadeesan… - Journal of the American …, 2017 - Elsevier
Diseases of the cerebral vasculature represent a heterogeneous group of ischemic and
hemorrhagic etiologies, which often manifest clinically as an acute neurologic deficit also …

Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location

FJ Detmer, BJ Chung, C Jimenez, F Hamzei-Sichani… - Neuroradiology, 2019 - Springer
Purpose The mechanisms of cerebral aneurysm rupture are not fully understood. We
analyzed the associations of hemodynamics, morphology, and patient age and gender with …

Development and internal validation of an aneurysm rupture probability model based on patient characteristics and aneurysm location, morphology, and …

FJ Detmer, BJ Chung, F Mut, M Slawski… - International journal of …, 2018 - Springer
Purpose Unruptured cerebral aneurysms pose a dilemma for physicians who need to weigh
the risk of a devastating subarachnoid hemorrhage against the risk of surgery or …

Association between hemodynamic conditions and occlusion times after flow diversion in cerebral aneurysms

F Mut, M Raschi, E Scrivano, C Bleise… - Journal of …, 2015 - jnis.bmj.com
Background Evaluation of flow diversion treatment of intracranial aneurysms is difficult
owing to lack of knowledge of the target hemodynamic environment. Objective To identify …

Morphologic and hemodynamic analysis in the patients with multiple intracranial aneurysms: ruptured versus unruptured

L Jing, J Fan, Y Wang, H Li, S Wang, X Yang, Y Zhang - PloS one, 2015 - journals.plos.org
Background and Purpose The authors evaluated the impact of morphologic and
hemodynamic factors on multiple intracranial aneurysms and aimed to identify which …

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

P Berg, S Saalfeld, S Voß, O Beuing, G Janiga - Neurosurgical focus, 2019 - thejns.org
Computational blood flow modeling in intracranial aneurysms (IAs) has enormous potential
for the assessment of highly resolved hemodynamics and derived wall stresses. This results …

[HTML][HTML] Imaging modalities for intracranial aneurysm: more than meets the eye

C Maupu, H Lebas, Y Boulaftali - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Intracranial aneurysms (IA) are often asymptomatic and have a prevalence of 3 to 5% in the
adult population. The risk of IA rupture is low, however when it occurs half of the patients …

Lattice Boltzmann model for simulation of flow in intracranial aneurysms considering non-Newtonian effects

SA Hosseini, F Huang, D Thévenin - Physics of Fluids, 2022 - pubs.aip.org
We propose a robust modified central Hermite polynomial-based multiple relaxation time
lattice Boltzmann model with independent control over relaxation of acoustic modes for non …

Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …