Mechanism of action and biology of flow diverters in the treatment of intracranial aneurysms

K Ravindran, AM Casabella, J Cebral, W Brinjikji… - …, 2020 - journals.lww.com
Flow diverters have drastically changed the landscape of intracranial aneurysm treatment
and are now considered first-line therapy for select lesions. Their mechanism of action relies …

Safety and efficacy results of the Flow Redirection Endoluminal Device (FRED) stent system in the treatment of intracranial aneurysms: US pivotal trial

CG McDougall, O Diaz, A Boulos… - Journal of …, 2022 - jnis.bmj.com
Objective To evaluate the safety and effectiveness of the Flow Redirection Endoluminal
Device (FRED) flow diverter in support of an application for Food and Drug Administration …

Promoting endothelialization of flow-diverting stents: a review

K Panchendrabose, S Muram, AP Mitha - Journal of …, 2021 - jnis.bmj.com
Intracranial flow-diverting (FD) stents have revolutionized the treatment of intracranial
aneurysms in recent years, but complications resulting from failed endothelialization can still …

[HTML][HTML] Vascular response on a novel fibrin-based coated flow diverter

R Mühl-Benninghaus, F Fries, M Kießling… - Cardiovascular and …, 2022 - Springer
Purpose Due to thromboembolic complications and in-stent-stenosis after flow diverter (FD)
treatment, the long-term use of dual antiplatelet treatment (DAPT) is mandatory. The tested …

Outcome of flow diverter placement for intracranial aneurysm with dual antiplatelet therapy and oral anticoagulant therapy

T Fujii, H Oishi, K Teranishi, K Yatomi… - Interventional …, 2020 - journals.sagepub.com
Purpose Antiplatelet therapy initiated before flow diverter placement is effective for the
prevention of ischemic complications. However, the effectiveness of oral anticoagulant …

Lumen-oriented versus wall-oriented treatment strategies for intracranial aneurysms–A systematic review of suggested therapeutic concepts

BE Grüter, F von Faber-Castell… - Journal of Cerebral …, 2022 - journals.sagepub.com
The development of new treatment strategies for intracranial aneurysms (IAs) has been and
continues to be a major interest in neurovascular research. Initial treatment concepts were …

Magnetic particle imaging for artifact-free imaging of intracranial flow diverter stents: A phantom study

M Herzberg, F Dorn, P Dietrich, MA Rückert, T Kampf… - Physica Medica, 2021 - Elsevier
Abstract Purpose Magnetic Particle Imaging (MPI) is a new, background-and radiation-free
tomographic imaging method that enables near real-time imaging of superparamagnetic …

Testing stenting and flow diversion using a surgical elastase-induced complex fusiform aneurysm model

R Fahed, TE Darsaut, I Salazkin… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Rabbit elastase-induced saccular aneurysms have been
commonly used for preclinical testing of endovascular devices, including flow diverters …

Evaluation of a novel flow diverter, the DiVeRt system, in an animal model

C Hufnagl, E Broussalis, C Cognard, J Grimm… - Journal of …, 2022 - jnis.bmj.com
Background Using a surgical aneurysm model, this study assessed the performance of a
new flow diverter (FD), the DiVeRt, and evaluated the angiographic and histologic features …

The new generation double layered flow diverters for endovascular treatment of intracranial aneurysms: current status of ongoing clinical uses

O Pavlov, A Shrivastava… - Expert Review of …, 2021 - Taylor & Francis
Introduction The treatment of intracranial aneurysms has significantly evolved over the last
decade with the advancement in endovascular techniques and devices. Flow diverters are …