Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines

M Filippi, P Preziosa, BL Banwell, F Barkhof… - Brain, 2019 - academic.oup.com
MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application

ME Ladd, P Bachert, M Meyerspeer, E Moser… - Progress in nuclear …, 2018 - Elsevier
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

[HTML][HTML] Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

A Dal-Bianco, G Grabner, C Kronnerwetter… - Acta …, 2017 - Springer
In multiple sclerosis (MS), iron accumulates inside activated microglia/macrophages at
edges of some chronic demyelinated lesions, forming rims. In susceptibility-based magnetic …

[HTML][HTML] Cerebral iron deposition in neurodegeneration

P Dusek, T Hofer, J Alexander, PM Roos, JO Aaseth - Biomolecules, 2022 - mdpi.com
Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Value of 3T susceptibility-weighted imaging in the diagnosis of multiple sclerosis

MA Clarke, D Pareto… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Previous studies have suggested that the central vein sign
and iron rims are specific features of MS lesions. Using 3T SWI, we aimed to compare the …

The clinical utility of QSM: disease diagnosis, medical management, and surgical planning

S Eskreis‐Winkler, Y Zhang, J Zhang, Z Liu… - NMR in …, 2017 - Wiley Online Library
Quantitative susceptibility mapping (QSM) is an MR technique that depicts and quantifies
magnetic susceptibility sources. Mapping iron, the dominant susceptibility source in the …

Quantifying iron content in magnetic resonance imaging

K Ghassaban, S Liu, C Jiang, EM Haacke - Neuroimage, 2019 - Elsevier
Measuring iron content has practical clinical indications in the study of diseases such as
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …

What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?

MS Martire, L Moiola, MA Rocca, M Filippi… - Expert review of …, 2022 - Taylor & Francis
Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

[HTML][HTML] Ultra-high-field 7-T MRI in multiple sclerosis and other demyelinating diseases: from pathology to clinical practice

N Bruschi, G Boffa, M Inglese - European radiology experimental, 2020 - Springer
Magnetic resonance imaging (MRI) is essential for the early diagnosis of multiple sclerosis
(MS), for investigating the disease pathophysiology, and for discriminating MS from other …

Imaging chronic active lesions in multiple sclerosis: a consensus statement

F Bagnato, P Sati, CC Hemond, C Elliott, SA Gauthier… - Brain, 2024 - academic.oup.com
Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …