Metals are involved in different pathophysiological mechanisms associated with
neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

Iron is involved in many processes in the brain including, myelin generation, mitochondrial
function, synthesis of ATP and DNA and the cycling of neurotransmitters. Disruption of …

The imbalance in the concentration of metallic nanoparticles has been demonstrated to play
an important role in multiple sclerosis (MS), which may impact cognition. Biomarkers are …

Multiple sclerosis (MS) is primarily an inflammatory and degenerative disease of the central
nervous system, triggered by unknown environmental factors in patients with predisposing …

Recent advances in susceptibility MRI have dramatically improved the visualization of deep
gray matter brain regions and the quantification of their magnetic properties in vivo …

Cognitive impairment is a frequent and meaningful symptom in multiple sclerosis (MS),
caused by the accrual of brain structural damage only partially counteracted by effective …

Iron accumulates with age in the normal human brain. This process is altered at several
levels in the brain of multiple sclerosis (MS) patients. Since iron is mainly stored in …

BACKGROUND AND PURPOSE: Modifications of magnetic susceptibility have been
consistently demonstrated in the subcortical gray matter of MS patients, but some …