Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Quantitative susceptibility mapping (QSM) and effective transverse relaxation rate (R2*)
mapping are both highly sensitive to variations in brain iron content. Clinical Magnetic …

Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

Purpose To study deep gray matter susceptibility in multiple sclerosis (MS) by using
quantitative susceptibility mapping (QSM) and to assess the relationship between …

Background MRI is a sensitive method for the assessment of brain abnormalities in Wilson
disease, that is, T2 hyperintensities, T2 hypointensities, and atrophy, but a validated scoring …

Increased brain iron concentration is often reported concurrently with disease development
in multiple sclerosis (MS) and other neurodegenerative diseases. However, it is unclear …

Recent advances in susceptibility MRI have dramatically improved the visualization of deep
gray matter brain regions and the quantification of their magnetic properties in vivo …

This review is a condensed summary of representative articles addressing the sex/gender
bias in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). The …

The link between white matter hyperintensities (WMH) and cortical thinning is thought to be
an important pathway by which WMH contributes to cognitive deficits in cerebral small …