White matter loss and oligodendrocyte dysfunction in HIV: a consequence of the infection, the antiretroviral therapy or both?
While the severe cognitive effects of HIV-associated dementia have been reduced by
combined antiretroviral therapy (cART), nearly half of HIV-positive (HIV+) patients still suffer …
combined antiretroviral therapy (cART), nearly half of HIV-positive (HIV+) patients still suffer …
Metabolic syndrome and cardiovascular disease impacts on the pathophysiology and phenotype of HIV-associated neurocognitive disorders
A Moulignier, D Costagliola - Neurocognitive Complications of HIV …, 2020 - Springer
Evidence from epidemiological studies on the general population suggests that midlife
cardiovascular disease (CVD) and/or metabolic syndrome (MetS) are associated with an …
cardiovascular disease (CVD) and/or metabolic syndrome (MetS) are associated with an …
Multishell diffusion MRI reveals whole‐brain white matter changes in HIV
Diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) have been previously
used to explore white matter related to human immunodeficiency virus (HIV) infection. While …
used to explore white matter related to human immunodeficiency virus (HIV) infection. While …
Brain structural changes following HIV infection: meta-analysis
EE O'connor, TA Zeffiro… - American Journal of …, 2018 - Am Soc Neuroradiology
BACKGROUND: Numerous studies have used structural neuroimaging to measure HIV
effects on brain macroarchitecture. While many have reported changes in total brain volume …
effects on brain macroarchitecture. While many have reported changes in total brain volume …
Effects of comorbidity burden and age on brain integrity in HIV
Objective: The influence of confounding neurocognitive comorbidities in people living with
HIV (PLWH) on neuroimaging has not been systematically evaluated. We determined …
HIV (PLWH) on neuroimaging has not been systematically evaluated. We determined …
Altered gray matter volume and functional connectivity in human immunodeficiency virus-infected adults
D Liu, C Zhao, W Wang, Y Wang, R Li, J Sun… - Frontiers in …, 2020 - frontiersin.org
People living with human immunodeficiency virus (HIV)(PLWH) are at high risk of
neurocognitive impairment. The pathogenesis of neurocognitive impairment remains …
neurocognitive impairment. The pathogenesis of neurocognitive impairment remains …
The structural and functional correlates of frailty in persons with human immunodeficiency virus
Abstract Background Persons with HIV (PWH) are at increased risk of frailty, a clinically
recognizable state of increased vulnerability resulting from aging-associated decline in …
recognizable state of increased vulnerability resulting from aging-associated decline in …
The joint effect of aging and HIV infection on microstructure of white matter bundles
Recent evidence suggests the aging process is accelerated by HIV. Degradation of white
matter (WM) has been independently associated with HIV and healthy aging. Thus, WM may …
matter (WM) has been independently associated with HIV and healthy aging. Thus, WM may …
Axonal chronic injury in treatment-naïve HIV+ adults with asymptomatic neurocognitive impairment and its relationship with clinical variables and cognitive status
R Li, J Sun, Z Tang, J Zhang, H Li - BMC neurology, 2018 - Springer
Background HIV is a neurotropic virus, and it can bring about neurodegeneration and may
even result in cognitive impairments. The precise mechanism of HIV-associated white matter …
even result in cognitive impairments. The precise mechanism of HIV-associated white matter …
HIV disease and diabetes interact to affect brain white matter hyperintensities and cognition
Background: Since the onset of combination antiretroviral therapy use, the incidence of HIV-
associated dementia and of HIV encephalitis has fallen dramatically. The present study …
associated dementia and of HIV encephalitis has fallen dramatically. The present study …
