Introduction: Hemorrhagic transformation (HT) is a complication of reperfusion therapy for
acute ischemic stroke. Blood–brain barrier (BBB) disruption is a crucial step toward HT; …

Background: Blood–brain barrier permeability (BBBp) is a key process involved in ischemic
stroke pathophysiology. However, there is a lack of consensus on how BBBp evolves after …

Background and purpose In patients with acute ischemic stroke treated with reperfusion
therapy we aimed to evaluate whether pretreatment blood–brain barrier (BBB) leakage is …

Objective: Hemorrhagic transformation (HT) is the most severe complication of reperfusion
therapy in acute ischemic stroke (AIS) patients. Management of AIS patients could benefit …

Currently most acute ischemic stroke patients presenting with a large vessel occlusion are
treated with endovascular therapy (EVT), which results in high rates of successful …

Unfavorable venous outflow (VO) is associated with cerebral edema, which represents
microvascular dysfunction. This study estimated the relationship between VO and …

Objective To investigate the diagnostic performance of perfusion CT for prediction of
hemorrhagic transformation in acute ischemic stroke. Methods A computerized literature …

Background: Hemorrhagic transformation (HT) is a common complication of acute ischemic
stroke, often resulting from reperfusion therapy. Early prediction of HT can enable stroke …

Background: Early identification of patients developing symptomatic intracranial hemorrhage
and symptomatic brain edema after acute ischemic stroke is essential for clinical decision …

Hemorrhagic transformation (HT) is one of the most devastating complications of reperfusion
therapy in acute ischemic stroke. Prediction of an upcoming HT remains beyond current …