Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines

M Filippi, P Preziosa, BL Banwell, F Barkhof… - Brain, 2019 - academic.oup.com
MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

[HTML][HTML] Present and future of the diagnostic work-up of multiple sclerosis: the imaging perspective

M Filippi, P Preziosa, DL Arnold, F Barkhof… - Journal of …, 2023 - Springer
In recent years, the use of magnetic resonance imaging (MRI) for the diagnostic work-up of
multiple sclerosis (MS) has evolved considerably. The 2017 McDonald criteria show high …

Paramagnetic rim lesions are specific to multiple sclerosis: an international multicenter 3T MRI study

P Maggi, P Sati, G Nair, ICM Cortese… - Annals of …, 2020 - Wiley Online Library
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on
magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports …

What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?

MS Martire, L Moiola, MA Rocca, M Filippi… - Expert review of …, 2022 - Taylor & Francis
Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

[HTML][HTML] The use of the central vein sign in the diagnosis of multiple sclerosis: a systematic review and meta-analysis

M Castellaro, A Tamanti, AI Pisani, FB Pizzini… - Diagnostics, 2020 - mdpi.com
Background: The central vein sign (CVS) is a radiological feature proposed as a multiple
sclerosis (MS) imaging biomarker able to accurately differentiate MS from other white matter …

[HTML][HTML] Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues

F La Rosa, M Wynen, O Al-Louzi, ES Beck… - NeuroImage: Clinical, 2022 - Elsevier
The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …

[HTML][HTML] Intensity warping for multisite MRI harmonization

J Wrobel, ML Martin, R Bakshi, PA Calabresi, M Elliot… - NeuroImage, 2020 - Elsevier
In multisite neuroimaging studies there is often unwanted technical variation across
scanners and sites. These “scanner effects” can hinder detection of biological features of …

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

P Maggi, MJ Fartaria, J Jorge, F La Rosa… - NMR in …, 2020 - Wiley Online Library
The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS)
diagnosis, but its application in clinical routine is limited by inter‐rater variability and the …

Neurodegeneration in multiple sclerosis

GM Mey, KR Mahajan… - WIREs mechanisms of …, 2023 - Wiley Online Library
Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …

[HTML][HTML] From pathology to MRI and back: Clinically relevant biomarkers of multiple sclerosis lesions

H Kolb, O Al-Louzi, ES Beck, P Sati, M Absinta… - NeuroImage: Clinical, 2022 - Elsevier
Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …