Structural and functional brain imaging in long-term survivors of childhood acute lymphoblastic leukemia treated with chemotherapy: a systematic review

K Gandy, MA Scoggins, LM Jacola, M Litten… - JNCI Cancer …, 2021 - academic.oup.com
Background The effect of chemotherapy on brain development in long-term survivors of
pediatric acute lymphoblastic leukemia (ALL) was systematically reviewed. Methods A …

[HTML][HTML] Brain imaging in pediatric cancer survivors: correlates of cognitive impairment

SR Kesler, C Sleurs, BC McDonald… - Journal of clinical …, 2021 - ncbi.nlm.nih.gov
Pediatric cancer and its treatment are associated with increased risk for acute and chronic
cognitive impairments. Neuroimaging studies indicate a common biologic pathway of …

[HTML][HTML] Neurocognitive and behavioral outcomes of Chinese survivors of childhood lymphoblastic leukemia

L Peng, LS Yang, P Yam, CS Lam, AS Chan… - Frontiers in …, 2021 - frontiersin.org
Background Increasing attention has been dedicated to investigate modifiable risk factors of
late effects in survivors of childhood cancer. This study aims to evaluate neurocognitive and …

Evidence of association between obesity and lower cerebral myelin content in cognitively unimpaired adults

M Bouhrara, N Khattar, P Elango, SM Resnick… - International Journal of …, 2021 - nature.com
Background Myelin loss is a central feature of several neurodegenerative diseases,
including Alzheimer's disease (AD). In animal studies, a link has been established between …

[HTML][HTML] Association of markers of inflammation on attention and neurobehavioral outcomes in survivors of childhood acute lymphoblastic leukemia

YT Cheung, KKW To, R Hua, CP Lee, ASY Chan… - Frontiers in …, 2023 - frontiersin.org
Background: Survivors of childhood acute lymphoblastic leukemia (ALL) are at-risk of
developing cognitive impairment and neurobehavioral symptoms. Inflammation induced by …

Prevalence of leukoencephalopathy and its potential cognitive sequelae in cancer patients

G Schroyen, M Meylaers, S Deprez… - Journal of …, 2020 - Taylor & Francis
Due to the rising use of chemotherapy treatment in cancer patients and growing survival
rates, therapy-induced neurotoxic side effects are increasingly reported. Given the ambiguity …

[HTML][HTML] Age-and intravenous methotrexate-associated leukoencephalopathy and its neurological impact in pediatric patients with lymphoblastic leukemia

I Rijmenams, D Moechars, A Uyttebroeck, A Radwan… - Cancers, 2021 - mdpi.com
Simple Summary In this study, we investigated standardized post-chemotherapy magnetic
resonance (MR) scans for leukoencephalopathy and patient-and treatment-related risk …

Effects of chemotherapy for acute lymphoblastic leukemia on cognitive function in animal models of contemporary protocols: A systematic literature review

TC Alexander, KR Krull - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Survival rates of childhood acute lymphoblastic leukemia (ALL) have improved greatly due
to advanced therapies and supportive care. Intrathecal chemotherapy replaced cranial …

Characterization of leukoencephalopathy and association with later neurocognitive performance in pediatric acute lymphoblastic leukemia

JR Pryweller, JO Glass, ND Sabin… - Investigative …, 2021 - journals.lww.com
Objectives The most common form of pediatric cancer is acute lymphoblastic leukemia
(ALL). Magnetic resonance (MR) neuroimaging studies have revealed leukoencephalopathy …

Neural correlates of working memory function in pediatric cancer survivors treated with chemotherapy: an fMRI study

P Stefancin, C Cahaney, RI Parker… - NMR in …, 2020 - Wiley Online Library
The goal of this study is to investigate the neural correlates of working memory function
associated with chemotherapy in pediatric cancer survivors using event‐related functional …