• Using positron emission tomography, we studied cerebral glucose metabolism in drug-free,
age-and sex-matched, righthanded patients with unipolar depression (n= 10), bipolar …

Various brain imaging techniques have become available in the past decade. These include
techniques to evaluate brain structure, such as computed tomography and magnetic …

It has been widely demonstrated that schizophrenic patients show a broad range of deficits
in interpersonal skills. Recently, considerable attention has been focused on the ability of …

The effects of the indolehallucinogen psilocybin, a mixed 5-HT 2 and 5-HT 1 agonist, on
regional cerebral glucose metabolism were investigated in 10 healthy volunteers with PET …

• Cerebral metabolic rates for glucose were examined in patients with unipolar depression
(N= 11), bipolar depression (N= 5), mania (N= 5), bipolar mixed states (N= 3), and in normal …

• In a second large series of schizophrenic patients studied with magnetic resonance
imaging at the University of Iowa, Iowa City, earlier findings of decreased frontal, cerebral …

Twenty affective disorder patients (16 bipolar and 4 unipolar) and 24 normal controls
received scans with positron emission tomography (PET) using [18 F] 2-deoxyglucose (FDG) …

Cerebral metabolic hypofrontality in schizophrenia is a controversial research finding. In this
article we discuss some of the issues that fuel this controversy, and we speculate on the …

The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …

• In previous studies we found that patients with chronic schizophrenia had lower regional
cerebral blood flow (rCBF) in dorsolateral prefrontal cortex (DLPFC) than did normal …