A review is given of the development of the water-soluble contrast media (CM) with
particular attention to the frequency of neurological complications. A remarkable …

Since toxic effects have been more readily appreciated in other organ systems than within
the nervous system, it was easy to detect toxic anemia by measuring the hemoglobin …

Conventional water‐soluble iodine‐containing contrast media such as salts of diatrizoic and
iothalamic acids dissociate in solution resulting in preparations which are very high in …

Iopamidol is a new, non‐ionic, water‐soluble iodide contrast medium which has been
shown in clinical trials in man to produce fewer and milder side effects than metrizamide for …

Iohexol and iopamidol are new second-generation nonionic contrast media. We review their
physical/chemical properties and describe the improvements made over the first-generation …

An attempt was made to assess the usefulness of using an animal model to predict the
neural tolerability in man of iodinated contrast media (CM) in general, and of the new …

A case of acute encephalopathy after lumbar myelography is reported in a female aged 26
years. Fourteen hours after the procedure, the patient developed coma (GCS 6) and had …

Pathophysiology of adverse reactions occurring during myelography with non-ionic contrast
agents, such as iopamidol, seem related to their direct action on the nervous system. The …

The effect of metrizamide myelography on 90‐minute postmyelographic cerebrospinal fluid
(CSF) samples was evaluated in a paired crossover study in 16 normal dogs. Each dog …

Purpose: Iomeprol, a new nonionic iodinated compound for intravascular use, is being
evaluated as a myelographic contrast agent because of its low neurotoxicity. This study …