[HTML][HTML] A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration

M Roy-O'Reilly, A Mulavara, T Williams - npj Microgravity, 2021 - nature.com
During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts

G Barisano, F Sepehrband… - Proceedings of the …, 2022 - National Acad Sciences
Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

[HTML][HTML] Advantages and limitations of current microgravity platforms for space biology research

F Ferranti, M Del Bianco, C Pacelli - Applied Sciences, 2020 - mdpi.com
Human Space exploration has created new challenges and new opportunities for science.
Reaching beyond the Earth's surface has raised the issue of the importance of gravity for the …

Sleep deficiency in spaceflight is associated with degraded neurobehavioral functions and elevated stress in astronauts on six-month missions aboard the …

CW Jones, M Basner, DJ Mollicone, CM Mott… - Sleep, 2022 - academic.oup.com
Astronauts are required to maintain optimal neurobehavioral functioning despite chronic
exposure to the stressors and challenges of spaceflight. Sleep of adequate quality and …

[HTML][HTML] Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight

KE Hupfeld, SB Richmond, HR McGregor… - Scientific reports, 2022 - nature.com
Humans are exposed to extreme environmental stressors during spaceflight and return with
alterations in brain structure and shifts in intracranial fluids. To date, no studies have …

A review of astronaut mental health in manned missions: Potential interventions for cognitive and mental health challenges

FA Oluwafemi, R Abdelbaki, JCY Lai… - Life sciences in space …, 2021 - Elsevier
Abstract Space is an isolated, confined environment for humans. These conditions can have
numerous effects on astronaut mental health and safety. Psychological and social issues …

Macro-and microstructural changes in cosmonauts' brains after long-duration spaceflight

S Jillings, A Van Ombergen, E Tomilovskaya… - Science …, 2020 - science.org
Long-duration spaceflight causes widespread physiological changes, although its effect on
brain structure remains poorly understood. In this work, we acquired diffusion magnetic …

Spaceflight associated neuro-ocular syndrome (SANS): A systematic review and future directions

Y Martin Paez, LI Mudie, PS Subramanian - Eye and Brain, 2020 - Taylor & Francis
Purpose To present a systematic review of the current body of literature surrounding
spaceflight associated neuro-ocular syndrome (SANS) and highlight priorities for future …

[HTML][HTML] The burden of space exploration on the mental health of astronauts: a narrative review

A Arone, T Ivaldi, K Loganovsky, S Palermo… - Clinical …, 2021 - ncbi.nlm.nih.gov
Abstract Space travel, a topic of global interest, has always been a fascinating matter, as its
potential appears to be infinite. The development of advanced technologies has made it …