Studies of the retinal microcirculation using human donor eyes and high-resolution clinical imaging: insights gained to guide future research in diabetic retinopathy

C Balaratnasingam, D An, M Hein, P Yu… - Progress in Retinal and …, 2023 - Elsevier
The microcirculation plays a key role in delivering oxygen to and removing metabolic wastes
from energy-intensive retinal neurons. Microvascular changes are a hallmark feature of …

From 2D to 4D phase‐contrast MRI in the neurovascular system: will it be a quantum jump or a fancy decoration?

SW Youn, J Lee - Journal of Magnetic Resonance Imaging, 2022 - Wiley Online Library
Considering the crosstalk between the flow and vessel wall, hemodynamic assessment of
the neurovascular system may offer a well‐integrated solution for both diagnosis and …

[HTML][HTML] SRflow: Deep learning based super-resolution of 4D-flow MRI data

S Shit, J Zimmermann, I Ezhov, JC Paetzold… - Frontiers in Artificial …, 2022 - frontiersin.org
Exploiting 4D-flow MRI data to quantify hemodynamics requires an adequate spatio-
temporal vector field resolution at a low noise level. To address this challenge, we provide a …

Dynamic modes of inflow jet in brain aneurysms

TB Le - Journal of Biomechanics, 2021 - Elsevier
The transition of the inflow jet to turbulence is crucial in understanding the pathology of brain
aneurysms. Previous works Le et al.(2010, 2013) have shown evidence for a highly dynamic …

Accelerated dual‐venc 4D flow MRI with variable high‐venc spatial resolution for neurovascular applications

M Aristova, J Pang, Y Ma, L Ma… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose Dual‐velocity encoded (dual‐venc or DV) 4D flow MRI achieves wide velocity
dynamic range and velocity‐to‐noise ratio (VNR), enabling accurate neurovascular flow …

Computational fluid–structure interactions in the human cerebrovascular system: Part 2—A review of current applications of computational fluid dynamics and …

R Achey, N Thiyagarajah… - … and Science in …, 2022 - asmedigitalcollection.asme.org
The cerebrovascular system is an intricate structure that carries blood to and from the brain.
Though the overall structures remain relatively the same from person to person, variations of …

Inflow hemodynamics of intracranial aneurysms: a comparison of computational fluid dynamics and 4D flow magnetic resonance imaging

K Misaki, K Futami, T Uno, I Nambu… - Journal of Stroke and …, 2021 - Elsevier
Purpose Although the inflow hemodynamics of cerebral aneurysms are key factors in their
rupture and recurrence after endovascular treatments, the most available method for inflow …

Minimum wall shear stress points and their underlying intra-aneurysmal flow structures of unruptured cerebral aneurysms on 4D flow MRI

K Futami, K Misaki, T Uno, I Nambu, T Tsutsui… - Journal of …, 2023 - Elsevier
Background and purpose Minimum wall shear stress (Min-WSS) points may be associated
with wall instability of unruptured cerebral aneurysms. We aimed to investigate the …

[HTML][HTML] Influence of vortical structures on fibrin clot formation in cerebral aneurysms: A two-dimensional computational study

T Ngwenya, D Grundlingh, MN Ngoepe - Journal of Biomechanics, 2024 - Elsevier
Thrombosis is an important contributor to cerebral aneurysm growth and progression. A
number of sophisticated multiscale and multiphase in silico models have been developed …

Clinical Applications of Four-Dimensional Flow MRI

A Maroun, S Quinn, D Dushfunian… - Magnetic …, 2023 - mri.theclinics.com
Phase contrast (PC) MR imaging (MRI) is a technique used to visualize and quantify moving
fluid. 1 Since its introduction in the late 1980s, it has received broad clinical acceptance for …