Abstract Introduction/Aims Intrathecal administration of nusinersen is challenging in patients
with spinal muscular atrophy (SMA) who have spine deformities or fusions. We prospectively …

Fluoroscopic-guided lumbar puncture (LP) is a procedure commonly performed by
radiologists, which in some circumstances may be difficult or impossible using a traditional …

Background Spinal deformity and prior spinal fusion pose technical challenges to lumbar
puncture (LP) for nusinersen administration for patients with spinal muscular atrophy (SMA) …

Background Nusinersen is the only approved treatment for all spinal muscular atrophy
(SMA) subtypes and is delivered intrathecally. Distorted spinal anatomy and instrumentation …

Percutaneous transforaminal lumbar punctures (TFLPs) offer alternative access routes to the
lumbar subarachnoid cistern. Safe fluoroscopic insertion of a needle through a lumbar …

Background The treatment of spinal muscular atrophy (SMA) with nusinersen requires
intrathecal medication administration, which can be challenging in individuals with …

Background and purpose The purpose was to investigate our centre's experience on
computed‐tomography‐guided (CT‐guided), transforaminal, intrathecal administration of …

A standard lumbar puncture may be impossible for many anatomic or technical reasons.
Previous accounts of caudal epidural anesthesia and other procedures via the sacral hiatus …

BACKGROUND: Spinal muscular atrophy is a progressive neurodegenerative disorder that
can be treated with intrathecal antisense oligonucleotide therapy (nusinersen). However …

Background Spinal administration of medications is challenging in patients with complete
posterior spinal fusion. We describe percutaneous image-guided intrathecal port placement …