[HTML][HTML] Imaging diagnosis and treatment selection for brain tumors in the era of molecular therapeutics

S Vagvala, JP Guenette, C Jaimes, RY Huang - Cancer Imaging, 2022 - Springer
Currently, most CNS tumors require tissue sampling to discern their molecular/genomic
landscape. However, growing research has shown the powerful role imaging can play in …

[HTML][HTML] Imaging-genomics in glioblastoma: Combining molecular and imaging signatures

D Liu, J Chen, X Hu, K Yang, Y Liu, G Hu, H Ge… - Frontiers in …, 2021 - frontiersin.org
Based on artificial intelligence (AI), computer-assisted medical diagnosis can scientifically
and efficiently deal with a large quantity of medical imaging data. AI technologies including …

[HTML][HTML] CT-based radiomics signature with machine learning predicts MYCN amplification in pediatric abdominal neuroblastoma

X Chen, H Wang, K Huang, H Liu, H Ding… - Frontiers in …, 2021 - frontiersin.org
Purpose MYCN amplification plays a critical role in defining high-risk subgroup of patients
with neuroblastoma. We aimed to develop and validate the CT-based machine learning …

[HTML][HTML] Conventional MRI features can predict the molecular subtype of adult grade 2–3 intracranial diffuse gliomas

A Lasocki, ME Buckland, KJ Drummond, H Wei, J Xie… - Neuroradiology, 2022 - Springer
Purpose Molecular biomarkers are important for classifying intracranial gliomas, prompting
research into correlating imaging with genotype (“radiogenomics”). A limitation of the …

The role of 2-hydroxyglutarate magnetic resonance spectroscopy for the determination of isocitrate dehydrogenase status in lower grade gliomas versus glioblastoma …

A Bhandari, C Sharma, M Ibrahim, M Riggs, R Jones… - Neuroradiology, 2021 - Springer
Purpose Magnetic resonance spectroscopy (MRS) provides a non-invasive means of
determining isocitrate dehydrogenase (IDH) status. Determination of 2-hydroxyglutarate (2 …

[HTML][HTML] Assessment of artificial intelligence (AI) reporting methodology in glioma MRI studies using the Checklist for AI in Medical Imaging (CLAIM)

A Bhandari, L Scott, M Weilbach, R Marwah, A Lasocki - Neuroradiology, 2023 - Springer
Abstract Purpose The Checklist for Artificial Intelligence in Medical Imaging (CLAIM) is a
recently released guideline designed for the optimal reporting methodology of artificial …

Machine learning imaging applications in the differentiation of true tumour progression from treatment‐related effects in brain tumours: A systematic review and meta …

A Bhandari, R Marwah, J Smith… - Journal of Medical …, 2022 - Wiley Online Library
Introduction Chemotherapy and radiotherapy can produce treatment‐related effects, which
may mimic tumour progression. Advances in Artificial Intelligence (AI) offer the potential to …

[HTML][HTML] Correlating MRI features with additional genetic markers and patient survival in histological grade 2-3 IDH-mutant astrocytomas

A Lasocki, ME Buckland, T Molinaro, J Xie, JR Whittle… - Neuroradiology, 2023 - Springer
Purpose The increasing importance of molecular markers for classification and
prognostication of diffuse gliomas has prompted the use of imaging features to predict …

[HTML][HTML] Multi-parametric radiomic model to predict 1p/19q co-deletion in patients with IDH-1 mutant glioma: added value to the T2-FLAIR mismatch sign

S Kihira, A Derakhshani, M Leung, K Mahmoudi… - Cancers, 2023 - mdpi.com
Simple Summary The T2-FLAIR mismatch sign has shown promise in determining IDH
mutant 1p/19q non-co-deleted diffuse gliomas with a high specificity and modest sensitivity …

MRI‐based deep learning techniques for the prediction of isocitrate dehydrogenase and 1p/19q status in grade 2–4 adult gliomas

D Kalaroopan, A Lasocki - Journal of Medical Imaging and …, 2023 - Wiley Online Library
Molecular biomarkers are becoming increasingly important in the classification of
intracranial gliomas. While tissue sampling remains the gold standard, there is growing …