Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Immunotherapy has become a fourth pillar in the treatment of brain tumors and, when
combined with radiation therapy, may improve patient outcomes and reduce the …

Sampling restrictions have hindered the comprehensive study of invasive non-enhancing
(NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present …

Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance
imaging (MRI) is particularly valuable as an amine‐and pH‐sensitive imaging technique in …

Purpose There remains no consensus normal-appearing white matter (NAWM)
normalization method to compute normalized relative cerebral blood volume (nrCBV) and …

Glioblastoma is the most aggressive type of primary adult brain tumour. The median survival
of patients with glioblastoma remains approximately 15 months, and the 5-year survival rate …

Neuroimaging plays a central role but still often falls short on essential questions. Advanced
imaging acquisition and analysis techniques hold great promise for answering such …

Despite decades of advancement in the diagnosis and therapy of gliomas, the most
malignant primary brain tumors, the overall survival rate is still dismal, and their post …

BACKGROUND AND PURPOSE: Differentiation between tumor and radiation necrosis in
patients with brain metastases treated with stereotactic radiosurgery is challenging. We …

In the follow-up of treated high-grade gliomas (HGG), differentiating true tumor progression
from treatment-related effects such as pseudoprogression and radiation necrosis presents …