Saturation transfer MRI for detection of metabolic and microstructural impairments underlying neurodegeneration in alzheimer's disease

A Orzyłowska, W Oakden - Brain Sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most common causes of dementia and difficult to
study as the pool of subjects is highly heterogeneous. Saturation transfer (ST) magnetic …

Multimodality imaging of neurodegenerative disorders with a focus on multiparametric magnetic resonance and molecular imaging

JR Loftus, S Puri, SP Meyers - Insights Into Imaging, 2023 - Springer
Neurodegenerative diseases afflict a large number of persons worldwide, with the
prevalence and incidence of dementia rapidly increasing. Despite their prevalence, clinical …

[HTML][HTML] Heritability of R2* iron in the basal ganglia and cortex

E Hofer, L Pirpamer, C Langkammer, C Tinauer… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Background: While iron is essential for normal brain functioning, elevated concentrations are
commonly found in neurodegenerative diseases and are associated with impaired cognition …

[HTML][HTML] Pattern of Altered Magnetization Transfer Rate in Alzheimer's Disease

W Duan, P Sehrawat, TD Zhou, JT Becker… - Journal of Alzheimer's …, 2022 - ncbi.nlm.nih.gov
Background: Biomarkers for Alzheimer's disease (AD) are crucial for early diagnosis and
treatment monitoring once disease modifying therapies become available. Objective: This …

MR Imaging of Neurodegeneration

TLS Benzinger, S Jindal - Molecular Imaging of Neurodegenerative …, 2023 - Springer
Neurodegeneration is an acquired clinical syndrome involving cognitive impairments,
predominantly in memory and executive functions, in turn affecting activities of daily living …