Introduction Globally, women with dementia have a higher disease burden than men with
dementia. In addition, women with diabetes especially are at higher risk for cognitive …

Background Emerging evidence revealed that gut microbial dysbiosis is involved in the
pathogenesis of multiple neurological diseases, but there is little available data on the …

Brain spaces around (perivascular spaces) and alongside (paravascular or Virchow–Robin
spaces) vessels have gained significant attention in recent years due to the advancements …

Background Current methods for quantitative assessment of cerebral small vessel disease
(CSVD) ignore critical aspects of the disease, namely lesion type and regionality. We …

The impact of small vessel disease (SVD) on stroke outcome was investigated either
separately for its single features in isolation or for SVD sum score measuring a qualitative …

Background Both cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA)
are related to cognitive impairment and dementia. This study aimed to clarify CAA-and HA …

Type 2 diabetes is consistently reported to be associated with reduced gray matter, mainly in
the cortical-striatal-limbic networks. However, little is known about how the progression of …

Purpose The plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) is an inflammatory
biomarker of cerebral microbleeds (CMBs) and may be related to the occurrence …

More than 2 million young adults (15–55 years old) have an ischemic stroke yearly
worldwide, 1 and the incidence is increasing. 2 Modifiable risk factors account for almost …

Cerebral small vessel disease (SVD) is a major underlying cause not only of ischemic and
hemorrhagic stroke but also of cognitive impairment and dementia (1). It includes several …