Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain

EO Major, K Amemiya, CS Tornatore… - Clinical microbiology …, 1992 - Am Soc Microbiol
Studies of the pathogenesis and molecular biology of JC virus infection over the last two
decades have significantly changed our understanding of progressive multifocal …

JC virus infection of the brain

AK Bag, JK Curé, PR Chapman… - American Journal …, 2010 - Am Soc Neuroradiology
Since its initial description, there have been significant changes in the epidemiology,
pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most …

Imaging manifestations of progressive multifocal leukoencephalopathy

R Shah, AK Bag, PR Chapman, JK Curé - Clinical radiology, 2010 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by
reactivation of JC virus in immunosuppressed patients. The diagnosis is usually suggested …

Progressive multifocal leukoencephalopathy in AIDS: are there any MR findings useful to patient management and predictive of patient survival?

MJD Post, C Yiannoutsos, D Simpson… - American Journal …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: While MR findings in progressive multifocal
leukoencephalopathy (PML) have been described previously, usually in retrospective …

[PDF][PDF] The clinical features of PML

JR Berger - Cleveland Clinic Journal of Medicine, 2011 - scholar.archive.org
■ ABSTRACT The symptoms associated with progressive multifocal leukoencephalopathy
(PML) reflect the location of pathologic brain lesions. These symptoms include visual …

The imaging appearances of intracranial CNS infections in adult HIV and AIDS patients

CE Offiah, IW Turnbull - Clinical radiology, 2006 - Elsevier
The spectrum of pathology affecting the central nervous system (CNS) in patients suffering
from acquired immunodeficiency syndrome (AIDS) is broad and comprises predominantly …

Progressive multifocal leukoencephalopathy: clinical and molecular aspects

E Tavazzi, MK White, K Khalili - Reviews in Medical Virology, 2012 - Wiley Online Library
The fatal CNS demyelinating disease, progressive multifocal leukoencephalopathy (PML), is
rare and appears to occur almost always as a consequence of immune dysfunction. Thus, it …

Progressive multifocal leukoencephalopathy: diffusion-weighted imaging and pathological correlations

M Bergui, GB Bradac, KK Oguz, A Boghi, C Geda… - Neuroradiology, 2004 - Springer
We examined MRI of two patients with progressive multifocal leukoencephalopathy (PML),
including diffusion-weighted imaging (DWI), with calculation of apparent diffusion …

Progressive multifocal leukoencephalopathy in patients with AIDS: appearance on MR images.

AS Mark, SW Atlas - Radiology, 1989 - pubs.rsna.org
Progressive multifocal leukoencephalopathy (PML) is an uncommon demyelinating disease
that occurs in immunocompromised patients. The authors evaluated magnetic resonance …

[HTML][HTML] Progressive multifocal leukoencephalopathy: an unexpected complication of modern therapeutic monoclonal antibody therapies

E Tavazzi, P Ferrante, K Khalili - Clinical microbiology and infection, 2011 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disorder of the
central nervous system, caused by the reactivation of the ubiquitous JC virus. PML usually …