Neurotransmitter deficits from frontotemporal lobar degeneration

AG Murley, JB Rowe - Brain, 2018 - academic.oup.com
Frontotemporal lobar degeneration causes a spectrum of complex degenerative disorders
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …

The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

3D GABA imaging with real-time motion correction, shim update and reacquisition of adiabatic spiral MRSI

W Bogner, B Gagoski, AT Hess, H Bhat, MD Tisdall… - Neuroimage, 2014 - Elsevier
Gamma-aminobutyric acid (GABA) and glutamate (Glu) are the major neurotransmitters in
the brain. They are crucial for the functioning of healthy brain and their alteration is a major …

Pathological glutamatergic neurotransmission in Gilles de la Tourette syndrome

AS Kanaan, S Gerasch, I García-García, L Lampe… - Brain, 2017 - academic.oup.com
Gilles de la Tourette syndrome is a hereditary, neuropsychiatric movement disorder with
reported abnormalities in the neurotransmission of dopamine and γ-aminobutyric acid …

Whole-slice mapping of GABA and GABA+ at 7T via adiabatic MEGA-editing, real-time instability correction, and concentric circle readout

P Moser, L Hingerl, B Strasser, M Považan, G Hangel… - Neuroimage, 2019 - Elsevier
Abstract An adiabatic MEscher-GArwood (MEGA)-editing scheme, using asymmetric
hyperbolic secant editing pulses, was developed and implemented in a B 1+-insensitive, 1D …

[HTML][HTML] Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats

A Casado-Sainz, F Gudmundsen… - …, 2022 - nature.com
Dorsal striatal dopamine transmission engages the cortico-striato-thalamo-cortical (CSTC)
circuit, which is implicated in many neuropsychiatric diseases, including obsessive …

Glutamatergic and GABA-ergic abnormalities in First-episode depression. A 1-year follow-up 1H-MR spectroscopic study

M Draganov, Y Vives-Gilabert… - Journal of Affective …, 2020 - Elsevier
Background Previous magnetic resonance spectroscopic (MRS) studies have reported brain
metabolic abnormalities in Major Depressive Disorder (MDD). Nevertheless, results have …

Still NAAG'ing after all these years: the continuing pursuit of GCPII inhibitors

JJ Vornov, KR Hollinger, PF Jackson… - Advances in …, 2016 - Elsevier
Nearly two decades ago, Joe Coyle published a single-authored review with the provocative
title, The Nagging Question of the Function of N-Acetylaspartylglutamate (Coyle, 1997). In …

[HTML][HTML] Altered brain metabolism contributes to executive function deficits in school-aged children born very preterm

B Schnider, R Tuura, V Disselhoff, B Latal… - Pediatric …, 2020 - nature.com
Background Executive function deficits in children born very preterm (VPT) have been linked
to anatomical abnormalities in white matter and subcortical brain structures. This study …

[HTML][HTML] Longitudinal increases of brain metabolite levels in 5-10 year old children

MJ Holmes, FC Robertson, F Little, SR Randall… - PLoS …, 2017 - journals.plos.org
Longitudinal magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) studies
reveal significant changes in brain structure and structural networks that occur together with …