Classification, diagnosis, and differential diagnosis of multiple sclerosis

IK Sand - Current opinion in neurology, 2015 - journals.lww.com
Current multiple sclerosis phenotypic classifications include relapsing-remitting multiple
sclerosis, clinically isolated syndrome, radiologically isolated syndrome, primary …

Brain mapping in multiple sclerosis: lessons learned about the human brain

M Filippi, P Preziosa, MA Rocca - Neuroimage, 2019 - Elsevier
The application of structural and functional magnetic resonance imaging (MRI) techniques in
patients with multiple sclerosis (MS) has certainly helped to improve our understanding of …

[HTML][HTML] The impact of epilepsy surgery on the structural connectome and its relation to outcome

PN Taylor, N Sinha, Y Wang, SB Vos, J de Tisi… - NeuroImage: Clinical, 2018 - Elsevier
Background Temporal lobe surgical resection brings seizure remission in up to 80% of
patients, with long-term complete seizure freedom in 41%. However, it is unclear how …

[HTML][HTML] Predicting language outcomes after stroke: Is structural disconnection a useful predictor?

TMH Hope, AP Leff, CJ Price - NeuroImage: Clinical, 2018 - Elsevier
For many years, researchers have sought to understand whether and when stroke survivors
with acquired language impairment (aphasia) will recover. There is broad agreement that …

Structural connectome disruption at baseline predicts 6‐months post‐stroke outcome

A Kuceyeski, BB Navi, H Kamel, A Raj… - Human brain …, 2016 - Wiley Online Library
In this study, models based on quantitative imaging biomarkers of post‐stroke structural
connectome disruption were used to predict six‐month outcomes in various domains …

The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation

L Xie, J Lv, K Saimaier, S Han, M Han, C Wang… - International …, 2023 - Elsevier
Multiple sclerosis (MS) is one of the most common autoimmune diseases of central nervous
system (CNS) demyelination. Experimental autoimmune encephalomyelitis (EAE) is the …

Structural disconnectivity from paramagnetic rim lesions is related to disability in multiple sclerosis

C Tozlu, K Jamison, T Nguyen, N Zinger… - Brain and …, 2021 - Wiley Online Library
Background In people with multiple sclerosis (pwMS), lesions with a hyperintense rim (rim+)
on Quantitative Susceptibility Mapping (QSM) have been shown to have greater myelin …

[HTML][HTML] Baseline biomarkers of connectome disruption and atrophy predict future processing speed in early multiple sclerosis

A Kuceyeski, E Monohan, E Morris, K Fujimoto… - NeuroImage: Clinical, 2018 - Elsevier
The development of accurate prognoses in multiple sclerosis is difficult, as the disease is
characterized by heterogeneous patterns of brain abnormalities that relate in an unclear way …

Regional white matter and gray matter damage and cognitive performances in multiple sclerosis according to sex

N Tedone, P Preziosa, A Meani, E Pagani… - Molecular …, 2023 - nature.com
In this study, we investigated whether regional distribution of white matter (WM) lesions,
normal-appearing [NA] WM microstructural abnormalities and gray matter (GM) atrophy may …

Profilometry: a new statistical framework for the characterization of white matter pathways, with application to multiple sclerosis

M Dayan, E Monohan, S Pandya… - Human brain …, 2016 - Wiley Online Library
Aims: describe a new “profilometry” framework for the multimetric analysis of white matter
tracts, and demonstrate its application to multiple sclerosis (MS) with radial diffusivity (RD) …