Unruptured intracranial aneurysms: development, rupture and preventive management

N Etminan, GJ Rinkel - Nature Reviews Neurology, 2016 - nature.com
Saccular unruptured intracranial aneurysms (UIAs) have a prevalence of 3% in the adult
population, and are being increasingly detected because of improved quality and higher …

Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms

J Frösen, J Cebral, AM Robertson, T Aoki - Neurosurgical focus, 2019 - thejns.org
OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …

Flow conditions in the intracranial aneurysm lumen are associated with inflammation and degenerative changes of the aneurysm wall

J Cebral, E Ollikainen, BJ Chung… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …

Risk factors for hemorrhage of brain arteriovenous malformation

SS Shaligram, E Winkler, D Cooke… - CNS neuroscience & …, 2019 - Wiley Online Library
Patients with brain arteriovenous malformation (bAVM) are at risk of intracranial hemorrhage
(ICH). Overall, bAVM accounts for 25% of hemorrhagic strokes in adults< 50 years of age …

How patient specific are patient-specific computational models of cerebral aneurysms? An overview of sources of error and variability

DA Steinman, VM Pereira - Neurosurgical focus, 2019 - thejns.org
Computational modeling of cerebral aneurysms, derived from clinical 3D angiography, has
become widespread over the past 15 years. While such “image-based” or “patient-specific” …

Relationship between aneurysm wall enhancement in vessel wall magnetic resonance imaging and rupture risk of unruptured intracranial aneurysms

N Lv, C Karmonik, S Chen, X Wang, Y Fang… - …, 2019 - journals.lww.com
BACKGROUND The rupture risk assessment of unruptured intracranial aneurysms (IAs) is
still challenging. Aneurysm wall enhancement (AWE) on vessel wall magnetic resonance …

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

P Berg, S Saalfeld, S Voß, O Beuing, G Janiga - Neurosurgical focus, 2019 - thejns.org
Computational blood flow modeling in intracranial aneurysms (IAs) has enormous potential
for the assessment of highly resolved hemodynamics and derived wall stresses. This results …

Fractional modeling of viscoelasticity in 3D cerebral arteries and aneurysms

Y Yu, P Perdikaris, GE Karniadakis - Journal of computational physics, 2016 - Elsevier
We develop efficient numerical methods for fractional order PDEs, and employ them to
investigate viscoelastic constitutive laws for arterial wall mechanics. Recent simulations …

Regional mapping of flow and wall characteristics of intracranial aneurysms

JR Cebral, X Duan, PS Gade, BJ Chung, F Mut… - Annals of biomedical …, 2016 - Springer
The evolution of intracranial aneurysms (IAs) is thought to be driven by progressive wall
degradation in response to abnormal hemodynamics. Previous studies focused on the …

[HTML][HTML] A review of hemodynamic parameters in cerebral aneurysm

MAA Sheikh, AS Shuib, MHH Mohyi - Interdisciplinary Neurosurgery, 2020 - Elsevier
A cerebral aneurysm is a localized dilation that weakens the wall of a blood vessel in the
brain. This condition comes in the form of abnormal widening, ballooning or in the form of a …