Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow
MJP van Osch, WM Teeuwisse… - Journal of Cerebral …, 2018 - journals.sagepub.com
With the publication in 2015 of the consensus statement by the perfusion study group of the
International Society for Magnetic Resonance in Medicine (ISMRM) and the EU-COST …
International Society for Magnetic Resonance in Medicine (ISMRM) and the EU-COST …
Neuroimaging of vascular reserve in patients with cerebrovascular diseases
MR Juttukonda, MJ Donahue - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity, defined broadly as the ability of brain parenchyma to adjust
cerebral blood flow in response to altered metabolic demand or a vasoactive stimulus, is …
cerebral blood flow in response to altered metabolic demand or a vasoactive stimulus, is …
Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging
This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a
wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) …
wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) …
[HTML][HTML] ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies
Arterial spin labeling (ASL) has undergone significant development since its inception, with
a focus on improving standardization and reproducibility of its acquisition and quantification …
a focus on improving standardization and reproducibility of its acquisition and quantification …
Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia
Blood transfusions are the mainstay of stroke prevention in pediatric sickle cell anemia
(SCA), but the physiology conferring this benefit is unclear. Cerebral blood flow (CBF) and …
(SCA), but the physiology conferring this benefit is unclear. Cerebral blood flow (CBF) and …
Diminished cerebral oxygen extraction and metabolic rate in sickle cell disease using T2 relaxation under spin tagging MRI
Purpose T2 MRI oximetry can noninvasively determine oxygen saturation (Y) but requires
empirical MR calibration models to convert the measured blood transverse relaxation (T2b) …
empirical MR calibration models to convert the measured blood transverse relaxation (T2b) …
Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia
Chronic transfusion therapy (CTT) prevents stroke in selected patients with sickle cell
anemia (SCA). We have shown that CTT mitigates signatures of cerebral metabolic stress …
anemia (SCA). We have shown that CTT mitigates signatures of cerebral metabolic stress …
[HTML][HTML] Impairment of cerebrovascular hemodynamics in patients with severe and milder forms of sickle cell disease
L Afzali-Hashemi, KPA Baas, A Schrantee… - Frontiers in …, 2021 - frontiersin.org
In patients with sickle cell disease (SCD), cerebral blood flow (CBF) is elevated to counteract
anemia and maintain oxygen supply to the brain. This may exhaust the vasodilating capacity …
anemia and maintain oxygen supply to the brain. This may exhaust the vasodilating capacity …
[HTML][HTML] Hemodynamic provocation with acetazolamide shows impaired cerebrovascular reserve in adults with sickle cell disease
L Václavů, BN Meynart, HJMM Mutsaerts… - …, 2019 - ncbi.nlm.nih.gov
Sickle cell disease is characterized by chronic hemolytic anemia and vascular inflammation,
which can diminish the vasodilatory capacity of the small resistance arteries, making them …
which can diminish the vasodilatory capacity of the small resistance arteries, making them …
White matter has impaired resting oxygen delivery in sickle cell patients
Although modern medical management has lowered overt stroke occurrence in patients with
sickle cell disease (SCD), progressive white matter (WM) damage remains common. It is …
sickle cell disease (SCD), progressive white matter (WM) damage remains common. It is …