Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …

The Sørensen-Dice index (SDI) is a widely used measure for evaluating medical image
segmentation algorithms. It offers a standardized measure of segmentation accuracy which …

The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …

Objective To determine the prognostic value of persisting neuroinflammation in multiple
sclerosis (MS) lesions, we developed a 18 kDa‐translocator‐protein‐positron emission …

Background Administration of a gadolinium-based contrast material is widely considered
obligatory for follow-up imaging of patients with multiple sclerosis (MS). However, advances …

Background and Objectives: In this critical review, we explore the potential use of MRI
measurements as prognostic biomarkers in multiple sclerosis (MS) patients, for both …

The specificity and implementation of current MRI-based diagnostic criteria for multiple
sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease
characterized by the appearance of focal lesions across the central nervous system. The …

Multiple sclerosis (MS) is a degenerative disease of the covering around the nerves in the
central nervous system. It damages the immune cells and causes small lesions in the …

Abstract Background and Purpose The presence of a paramagnetic rim around a white
matter lesion has recently been shown to be a hallmark of a particular pathological type of …