Genotoxic therapy and resistance mechanism in gliomas

F Lang, Y Liu, FJ Chou, C Yang - Pharmacology & therapeutics, 2021 - Elsevier
Glioma is one of the most common and lethal brain tumors. Surgical resection followed by
radiotherapy plus chemotherapy is the current standard of care for patients with glioma. The …

Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

[PDF][PDF] Reclassification of glioblastoma multiforme according to the 2021 World Health Organization classification of central nervous system tumors: a single institution …

GS Stoyanov, E Lyutfi, R Georgieva, R Georgiev… - Cureus, 2022 - cureus.com
The 2021 World Health Organization (WHO) classification of tumors of the central nervous
system (CNS) has introduced significant changes to tumor taxonomy. One of the most …

[HTML][HTML] Qualitative and quantitative magnetic resonance imaging phenotypes may predict CDKN2A/B homozygous deletion status in isocitrate dehydrogenase …

YW Park, KS Park, JE Park, SS Ahn, I Park… - Korean Journal of …, 2023 - ncbi.nlm.nih.gov
Objective Cyclin-dependent kinase inhibitor (CDKN) 2A/B homozygous deletion is a key
molecular marker of isocitrate dehydrogenase (IDH)-mutant astrocytomas in the 2021 World …

Diffusion-tensor imaging and dynamic susceptibility contrast MRIs improve radiomics-based machine learning model of MGMT promoter methylation status in …

TNT Minh, VH Le, NQK Le - Biomedical Signal Processing and Control, 2023 - Elsevier
Background Determining the O6-methylguanine-DNA methyltransferase (MGMT) promoter
methylation status, which is a predictor of response to standard radiotherapy treatment in …

Validation of MRI-based models to predict MGMT promoter methylation in gliomas: BraTS 2021 radiogenomics challenge

BH Kim, H Lee, KS Choi, JG Nam, CK Park, SH Park… - Cancers, 2022 - mdpi.com
Simple Summary O6-methylguanine-DNA methyl transferase (MGMT) methylation in
glioblastoma is an important prognostic and predictive factor that requires an invasive …

Multiparametric Framework Magnetic Resonance Imaging Assessment of Subtypes of Intracranial Germ Cell Tumors Using Susceptibility Weighted Imaging, Diffusion …

Y Li, P Wang, J Zhang, J Li, L Chen… - Journal of Magnetic …, 2022 - Wiley Online Library
Background Intracranial germ cell tumors (iGCTs) are classified into two pathological
subtypes (germinomas [GEs] and nongerminomatous germ cell tumors [NGGCTs]), with …

Hemodynamic Imaging in Cerebral Diffuse Glioma—Part B: Molecular Correlates, Treatment Effect Monitoring, Prognosis, and Future Directions

V Stumpo, L Guida, J Bellomo, CHB Van Niftrik… - Cancers, 2022 - mdpi.com
Simple Summary Cerebral diffuse gliomas present peculiar molecular features tightly linked
to phenotypic characteristics that are not readily appreciated by means of standard …

[HTML][HTML] Increased ASF1B expression correlates with poor prognosis in patients with gliomas

H Zhu, H Ouyang, X Pan, Z Zhang, J Tan, N Yu… - Frontiers in …, 2022 - frontiersin.org
Background: Recent studies have shown that Anti-silencing function 1 B (ASF1B) may be a
new potential marker of tumor prognosis. But the expression and function of ASF1B in …

Longitudinal study on MRI and neuropathological findings: Neither DSC-perfusion derived rCBVmax nor vessel densities correlate between newly diagnosed and …

E Steidl, K Filipski, E Hattingen, JP Steinbach… - Plos one, 2023 - journals.plos.org
Introduction When evaluating MRIs for glioblastoma progression, previous scans are usually
included into the review. Nowadays dynamic susceptibility contrast (DSC)-perfusion is an …