White matter abnormalities in multiple sclerosis evaluated by quantitative synthetic MRI, diffusion tensor imaging, and neurite orientation dispersion and density …

A Hagiwara, K Kamagata, K Shimoji… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A number of MR-derived quantitative metrics have been
suggested to assess the pathophysiology of MS, but the reports about combined analyses of …

MRI mean diffusivity detects widespread brain degeneration in multiple sclerosis

J Senda, H Watanabe, T Tsuboi, K Hara… - Journal of the …, 2012 - Elsevier
We investigated the magnetic resonance imaging (MRI) findings of 32 multiple sclerosis
(MS) patients using voxel-based morphometry (VBM) and voxel-based analysis of white …

Assessment of normal-appearing white and gray matter in patients with primary progressive multiple sclerosis: a diffusion-tensor magnetic resonance imaging study

M Rovaris, M Bozzali, G Iannucci, A Ghezzi… - Archives of …, 2002 - jamanetwork.com
Background Diffusion-tensor magnetic resonance imaging is sensitive to the more
destructive aspects of multiple sclerosis (MS) evolution occurring outside and within T2 …

[HTML][HTML] Comparison of neurite orientation dispersion and density imaging and two-compartment spherical mean technique parameter maps in multiple sclerosis

D Johnson, A Ricciardi, W Brownlee, B Kanber… - Frontiers in …, 2021 - frontiersin.org
Background: Neurite orientation dispersion and density imaging (NODDI) and the spherical
mean technique (SMT) are diffusion MRI methods providing metrics with sensitivity to similar …

Whole brain white matter changes revealed by multiple diffusion metrics in multiple sclerosis: a TBSS study

Y Liu, Y Duan, Y He, C Yu, J Wang, J Huang… - European journal of …, 2012 - Elsevier
OBJECTIVE: To investigate whole brain white matter changes in multiple sclerosis (MS) by
multiple diffusion indices, we examined patients with diffusion tensor imaging and utilized …

Relationships of brain white matter microstructure with clinical and MR measures in relapsing‐remitting multiple sclerosis

A Giorgio, J Palace, H Johansen‐Berg… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose: To assess the relationships of microstructural damage in the cerebral white matter
(WM), as measured by diffusion tensor imaging (DTI), with clinical parameters and magnetic …

Analysis of white matter damage in patients with multiple sclerosis via a novel in vivo MR method for measuring myelin, axons, and g-ratio

A Hagiwara, M Hori, K Yokoyama… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Myelin and axon volume fractions can now be estimated
via MR imaging in vivo, as can the g-ratio, which equals the ratio of the inner to the outer …

Multiple sclerosis: diffusion tensor MR imaging for evaluation of normal-appearing white matter

AC Guo, JR MacFall, JM Provenzale - Radiology, 2002 - pubs.rsna.org
PURPOSE: To determine whether the normal-appearing white matter (NAWM) regions
surrounding and remote from multiple sclerosis (MS) plaques have abnormal diffusional …

Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis

M Cercignani, M Inglese, E Pagani… - American journal of …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Compared with conventional T2-weighted MR imaging,
diffusion tensor MR imaging provides quantitative indices with increased specificity to the …

[HTML][HTML] Detecting white matter alterations in multiple sclerosis using advanced diffusion magnetic resonance imaging

SM Mustafi, J Harezlak, C Kodiweera… - Neural regeneration …, 2019 - journals.lww.com
Multiple sclerosis is a neurodegenerative and inflammatory disease, a hallmark of which is
demyelinating lesions in the white matter. We hypothesized that alterations in white matter …