Utility of a multiparametric quantitative MRI model that assesses myelin and edema for evaluating plaques, periplaque white matter, and normal-appearing white …
A Hagiwara, M Hori, K Yokoyama… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: T1 and T2 values and proton density can now be
quantified on the basis of a single MR acquisition. The myelin and edema in a voxel can …
quantified on the basis of a single MR acquisition. The myelin and edema in a voxel can …
Analysis of white matter damage in patients with multiple sclerosis via a novel in vivo MR method for measuring myelin, axons, and g-ratio
A Hagiwara, M Hori, K Yokoyama… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Myelin and axon volume fractions can now be estimated
via MR imaging in vivo, as can the g-ratio, which equals the ratio of the inner to the outer …
via MR imaging in vivo, as can the g-ratio, which equals the ratio of the inner to the outer …
[HTML][HTML] Modeling the presence of myelin and edema in the brain based on multi-parametric quantitative MRI
The aim of this study was to present a model that uses multi-parametric quantitative MRI to
estimate the presence of myelin and edema in the brain. The model relates simultaneous …
estimate the presence of myelin and edema in the brain. The model relates simultaneous …
Comparing MRI metrics to quantify white matter microstructural damage in multiple sclerosis
Quantifying white matter damage in vivo is becoming increasingly important for investigating
the effects of neuroprotective and repair strategies in multiple sclerosis (MS). While various …
the effects of neuroprotective and repair strategies in multiple sclerosis (MS). While various …
Characterization of white matter lesions in multiple sclerosis using proton density and T1-relaxation measures
Purpose Although lesion dissemination in time is a defining characteristic of multiple
sclerosis (MS), there is a limited understanding of lesion heterogeneity. Currently …
sclerosis (MS), there is a limited understanding of lesion heterogeneity. Currently …
White matter abnormalities in multiple sclerosis evaluated by quantitative synthetic MRI, diffusion tensor imaging, and neurite orientation dispersion and density …
BACKGROUND AND PURPOSE: A number of MR-derived quantitative metrics have been
suggested to assess the pathophysiology of MS, but the reports about combined analyses of …
suggested to assess the pathophysiology of MS, but the reports about combined analyses of …
[HTML][HTML] Measuring longitudinal myelin water fraction in new multiple sclerosis lesions
Objectives Investigating the potential of myelin repair strategies in multiple sclerosis (MS)
requires an understanding of myelin dynamics during lesion evolution. The objective of this …
requires an understanding of myelin dynamics during lesion evolution. The objective of this …
Dynamic contrast-enhanced magnetic resonance imaging suggests normal perfusion in normal-appearing white matter in multiple sclerosis
M Ingrisch, S Sourbron, S Herberich… - Investigative …, 2017 - journals.lww.com
Objectives Multiple sclerosis (MS) is a chronic, inflammatory disease of the central nervous
system and has been associated with reduced perfusion in normal-appearing white matter …
system and has been associated with reduced perfusion in normal-appearing white matter …
Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging
Damage to the myelin sheath and the neuroaxonal unit is a cardinal feature of multiple
sclerosis; however, a detailed characterization of the interaction between myelin and axon …
sclerosis; however, a detailed characterization of the interaction between myelin and axon …
Texture analysis of T2-weighted MR images to assess acute inflammation in brain MS lesions
N Michoux, A Guillet, D Rommel, G Mazzamuto… - PloS one, 2015 - journals.plos.org
Brain blood barrier breakdown as assessed by contrast-enhanced (CE) T1-weighted MR
imaging is currently the standard radiological marker of inflammatory activity in multiple …
imaging is currently the standard radiological marker of inflammatory activity in multiple …