BACKGROUND AND PURPOSE: Histopathologic studies have reported widespread cortical
lesions in MS; however, in vivo detection by using routinely available pulse sequences is …

Although significant improvements have been made regarding the visualization and
characterization of cortical multiple sclerosis (MS) lesions using magnetic resonance …

BACKGROUND AND PURPOSE: Multiple sclerosis (MS) is the most common inflammatory
disease of the central nervous system and manifests both physical and neurocognitive …

Background: Accurate classification of multiple sclerosis (MS) lesions in the brain cortex may
be important in understanding their impact on cognitive impairment (CI). Improved accuracy …

Importance Cortical lesions (CLs) contribute to physical and cognitive disability in multiple
sclerosis (MS). Accurate methods for visualization of CLs are necessary for future clinical …

Objectives The aim of this study was to evaluate the capability of sequences acquired on a 7-
T MRI scanner, within times and anatomical coverage appropriate for clinical studies, to …

Background Cortical lesions develop early in multiple sclerosis (MS) and play a major role in
disease progression. MRI at 7.0 T shows high sensitivity for detection of cortical lesions as …

PURPOSE: To prospectively compare the depiction of intracortical lesions by using multislab
three-dimensional (3D) double inversion-recovery (DIR), multislab 3D fluid-attenuated …

Background: Dramatic improvements in visualization of cortical (especially subpial) multiple
sclerosis (MS) lesions allow assessment of impact on clinical course. Objective …

BACKGROUND AND PURPOSE: Cortical lesions constitute a substantial part of the total
lesion load in multiple sclerosis (MS) brain. They have been related to neuropsychological …