Prospective safety study of intrathecal gadobutrol in different doses
A Sperre, I Karsrud, AHS Rodum… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In our clinical practice, we increasingly use intrathecal
contrast-enhanced glymphatic MR imaging to assess CSF disturbances. However, because …
contrast-enhanced glymphatic MR imaging to assess CSF disturbances. However, because …
[HTML][HTML] Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols
M Halvorsen, CS Edeklev, J Fraser-Green, G Løvland… - Neuroradiology, 2021 - Springer
Purpose Magnetic resonance imaging (MRI) contrast agents have been used off-label for
diagnosis of cerebrospinal fluid (CSF) leaks and lately also for assessment of the glymphatic …
diagnosis of cerebrospinal fluid (CSF) leaks and lately also for assessment of the glymphatic …
Intrathecal injection of gadobutrol: a tale of caution
C Reeves, E Galang, R Padalia, N Tran… - Journal of Pain & …, 2017 - Taylor & Francis
In the field of interventional pain medicine a radiocontrast agent is commonly used in
conjunction with fluoroscopy. Limited work has been published regarding the use of …
conjunction with fluoroscopy. Limited work has been published regarding the use of …
Intravenous injection of gadobutrol in an epidemiological study group did not lead to a difference in relative signal intensities of certain brain structures after 5 years
ML Kromrey, KR Liedtke, T Ittermann, S Langner… - European …, 2017 - Springer
Purpose To investigate if application of macrocyclic gadolinium-based contrast agents in
volunteers is associated with neuronal deposition detected by magnetic resonance imaging …
volunteers is associated with neuronal deposition detected by magnetic resonance imaging …
Safety and efficacy of gadobutrol for contrast-enhanced magnetic resonance imaging of the central nervous system: results from a multicenter, double-blind …
JE Gutierrez, M Rosenberg… - Magnetic …, 2015 - journals.sagepub.com
Purpose Contrast-enhanced magnetic resonance imaging (MRI) of the central nervous
system (CNS) with gadolinium-based contrast agents (GBCAs) is standard of care for CNS …
system (CNS) with gadolinium-based contrast agents (GBCAs) is standard of care for CNS …
[HTML][HTML] Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol
G Ringstad, LM Valnes, SAS Vatnehol, AH Pripp… - Neuroradiology, 2023 - Springer
Purpose A possible pathway behind gadolinium retention in brain is leakage of contrast
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …
MRI brain signal intensity and relaxation times in individuals with prior exposure to gadobutrol
M Saake, A Schmidle, M Kopp, J Hanspach, T Hepp… - Radiology, 2019 - pubs.rsna.org
Purpose To perform follow-up brain MRI in volunteer participants who had previously
received multiple doses of gadobutrol and to assess for changes in signal intensities and …
received multiple doses of gadobutrol and to assess for changes in signal intensities and …
[HTML][HTML] Safety of gadobutrol: results from 42 clinical phase II to IV studies and postmarketing surveillance after 29 million applications
J Endrikat, K Vogtlaender, S Dohanish… - Investigative …, 2016 - journals.lww.com
Objective The aim of this study was to provide a systematic safety analysis of gadobutrol
after more than 29 million applications in clinical routine. Materials and Methods Forty-two …
after more than 29 million applications in clinical routine. Materials and Methods Forty-two …
Accumulation of gadolinium in human cerebrospinal fluid after gadobutrol-enhanced MR imaging: a prospective observational cohort study
AK Nehra, RJ McDonald, AM Bluhm, TM Gunderson… - Radiology, 2018 - pubs.rsna.org
Purpose To determine whether gadolinium accumulates within cerebrospinal fluid (CSF) in
patients recently exposed to the macrocyclic agent gadobutrol and identify factors that may …
patients recently exposed to the macrocyclic agent gadobutrol and identify factors that may …
Intrathecal use of gadobutrol for glymphatic MR imaging: prospective safety study of 100 patients
CS Edeklev, M Halvorsen, G Løvland… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Intrathecal contrast-enhanced glymphatic MR imaging has
shown promise in assessing glymphatic function in patients with dementia. The purpose of …
shown promise in assessing glymphatic function in patients with dementia. The purpose of …
