BACKGROUND AND PURPOSE: Previous studies have shown involvement of both gray
matter (GM) and white matter (WM) in mild cognitive impairment (MCI) and Alzheimer …

OBJECTIVE: To assess whether structural brain damage as detected by magnetization
transfer imaging (MTI) in Alzheimer's disease (AD) and mild cognitive impairment (MCI) is …

BACKGROUND AND PURPOSE: Reductions in magnetization transfer ratio have been
associated with brain microstructural damage. We aim to compare magnetization transfer …

Purpose To explore the regional patterns of white matter (WM) tract damage in (a) patients
with probable Alzheimer disease (AD) and (b) patients with amnestic mild cognitive …

Almost half of the elderly subjects that are diagnosed with mild cognitive impairment (MCI)
go on to develop dementia of Alzheimer's type (DAT) over a 5-year follow-up. MCI and DAT …

Background: Conventional MRI can reveal decreases in brain volumes with aging but fails to
provide information about the underlying microstructural modifications. Magnetization …

BACKGROUND AND PURPOSE: Early stratification of degenerative processes is a
prerequisite to warrant therapeutic options in prodromal Alzheimer disease. Our aim was to …

ABSTRACT Background/Purpose: Gray matter involvement in multiple sclerosis (MS) is of
growing interest with respect to disease pathogenesis. Magnetization transfer imaging (MTI) …

Reduction in temporal lobe volume is consistently found in dementia of Alzheimer's type
(DAT). However, due to the lack of a consistent association between brain volume and …

Purpose To determine which MR technique was the most sensitive to age‐related white
matter damage. We compared both diffusion tensor imaging (DTI) and magnetization …