BACKGROUND AND PURPOSE: We used quantitative diffusion MR imaging to investigate
the microstructural changes that occur in white matter during normal aging in order to …

BACKGROUND AND PURPOSE: Quantifying changes in the human brain that occur as part
of normal aging may help in the diagnosis of diseases that affect the elderly and that cause …

Diffusion tensor imaging (DTI) was used to examine 1) age‐related changes in genu,
splenium, and centrum semiovale white matter diffusivity in 64 healthy men and women (age …

OBJECTIVE. The purpose of our study was to test the hypothesis that the apparent diffusion
coefficient (ADC) of normal-appearing white matter increases with advancing age …

With aging, the human brain tissue undergoes degeneration and a decline in cognitive
function. Diffusion tensor imaging (DTI) is a sensitive method for detecting microstructural …

The purpose of this study is to elucidate changes in mean diffusivity (ADC) and fractional
anisotropy (FA) using MR diffusion tensor imaging (DTI) in the central nervous system during …

Diffusion-weighted imaging (DWI) is a powerful new magnetic resonance imaging technique
for evaluating tissue pathophysiology in vivo. We performed DWI in three orthogonal spatial …

Introduction The aim of our work was to investigate the process of myelination in healthy
patients using the diffusion parameters apparent diffusion coefficient (ADC), relative …

We collected MRI diffusion tensor imaging data from 80 younger (20–32 years) and 63 older
(60–71 years) healthy adults. Tract-based spatial statistics (TBSS) analysis revealed that …

Age-related microstructural changes in brain white matter can be studied by utilizing indices
derived from diffusion tensor imaging (DTI): apparent diffusion coefficient (ADC) and …