Considerations for mean upper cervical cord area implementation in a longitudinal MRI setting: methods, interrater reliability, and MRI quality control

C Chien, V Juenger, M Scheel… - American Journal of …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Spinal cord atrophy is commonly measured from cerebral
MRIs, including the upper cervical cord. However, rescan intraparticipant measures have not …

Quantification of cervical cord cross-sectional area: which acquisition, vertebra level, and analysis software? A multicenter repeatability study on a traveling healthy …

C Lukas, B Bellenberg, F Prados, P Valsasina… - Frontiers in …, 2021 - frontiersin.org
Background: Considerable spinal cord (SC) atrophy occurs in multiple sclerosis (MS). While
MRI-based techniques for SC cross-sectional area (CSA) quantification have improved over …

Multicenter validation of mean upper cervical cord area measurements from head 3D T1-weighted MR imaging in patients with multiple sclerosis

Y Liu, C Lukas, MD Steenwijk… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Spinal cord atrophy is a common and clinically relevant
characteristic in multiple sclerosis. We aimed to perform a multicenter validation study of …

Evaluation of intra‐and interscanner reliability of MRI protocols for spinal cord gray matter and total cross‐sectional area measurements

N Papinutto, RG Henry - Journal of Magnetic Resonance …, 2019 - Wiley Online Library
Background In vivo quantification of spinal cord atrophy in neurological diseases using MRI
has attracted increasing attention. Purpose To compare across different platforms the most …

Cervical spinal cord atrophy can be accurately quantified using head images

K Taheri, IM Vavasour, S Abel, LE Lee… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background Spinal cord atrophy provides a clinically relevant metric for monitoring MS.
However, the spinal cord is imaged far less frequently than brain due to artefacts and …

[HTML][HTML] Reliability of multi-parameter mapping (MPM) in the cervical cord: A multi-center multi-vendor quantitative MRI study

M Seif, T Leutritz, S Schading, T Emmengger, A Curt… - Neuroimage, 2022 - Elsevier
MRI based multicenter studies which target neurological pathologies affecting the spinal
cord and brain–including spinal cord injury (SCI)–require standardized acquisition protocols …

Cervical cord area measurement using volumetric brain magnetic resonance imaging in multiple sclerosis

Z Liu, Ö Yaldizli, M Pardini, V Sethi, H Kearney… - Multiple sclerosis and …, 2015 - Elsevier
Background In multiple sclerosis (MS), recent work suggests that cervical cord atrophy is
more consistently correlated with physical disability than brain white matter lesion load and …

Improved Assessment of Longitudinal Spinal Cord Atrophy in Multiple Sclerosis Using a Registration‐Based Approach: Relevance for Clinical Studies

P Valsasina, MA Horsfield, A Meani… - Journal of Magnetic …, 2022 - Wiley Online Library
Background Reliable measurements of cervical cord atrophy progression may be useful for
monitoring neurodegeneration in multiple sclerosis (MS). Purpose To compare a new …

Reliable volumetry of the cervical spinal cord in MS patient follow-up data with cord image analyzer (Cordial)

M Amann, S Pezold, Y Naegelin, K Fundana… - Journal of …, 2016 - Springer
Spinal cord (SC) atrophy is an important contributor to the development of disability in many
neurological disorders including multiple sclerosis (MS). To assess the spinal cord atrophy …

Measurement of cervical spinal cord cross‐sectional area by MRI using edge detection and partial volume correction

CR Tench, PS Morgan… - Journal of Magnetic …, 2005 - Wiley Online Library
Purpose To detail a procedure to accurately measure upper cervical cord cross‐sectional
area (CSA), using MRI, by correcting for partial volume averaging (PVA), and to assess the …