Tyrosine kinase inhibitor therapy for brain metastases in non-small-cell lung cancer: a primer for radiologists

C Dodson, TJ Richards, DA Smith… - American Journal of …, 2020 - Am Soc Neuroradiology
Treatment options for patients who develop brain metastases secondary to non-small-cell
lung cancer have rapidly expanded in recent years. As a key adjunct to surgical and …

Indications and limitations of chemotherapy and targeted agents in non-small cell lung cancer brain metastases

S Zimmermann, R Dziadziuszko, S Peters - Cancer treatment reviews, 2014 - Elsevier
Lung cancer is characterized by the highest incidence of solid tumor-related brain
metastases, which are reported with a growing incidence during the last decade. Prognostic …

Emerging trends in the management of brain metastases from non-small cell lung cancer

TM Churilla, SE Weiss - Current Oncology Reports, 2018 - Springer
Abstract Purpose of Review To summarize current approaches in the management of brain
metastases from non-small cell lung cancer (NSCLC). Recent Findings Local treatment has …

Pharmacotherapeutic options for treating brain metastases in non-small cell lung cancer

G Metro, R Chiari, B Ricciuti, A Rebonato… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Central nervous system (CNS) metastases represent an important cause of
morbidity and mortality in non-small cell lung cancer (NSCLC) patients. Local approaches of …

Treating brain metastases in non-small cell lung cancer patients: what have we learnt from pharmaceutical recent clinical trials?

BC Liao, CC Lin, JCH Yang - Expert Opinion on Pharmacotherapy, 2018 - Taylor & Francis
ABSTRACT Introduction: Brain metastases (BMs) develop in up to 40% of patients with non-
small cell lung cancer (NSCLC). In many recent practice-changing clinical trials, patients …

Systemic therapies in the treatment of non-small-cell lung cancer brain metastases

RV Lukas, P Kumthekar, S Rizvi, R Salgia - Future Oncology, 2016 - Future Medicine
Non-small-cell lung cancer (NSCLC) brain metastases are common. Even though there are
various subsets of NSCLC with molecular alterations, there is a common theme of brain …

Up‐front chemotherapy and radiation treatment in newly diagnosed nonsmall cell lung cancer with brain metastases: Survey by Outcome Research Network for …

L Moscetti, F Nelli, A Felici, M Rinaldi, S De Santis… - Cancer, 2007 - Wiley Online Library
BACKGROUND. For patients with stage IV nonsmall cell lung cancer (NSCLC) who present
with brain metastasis (BMs), standard platinum‐based chemotherapy regimens have …

Multimodality management of non-small cell lung cancer patients with brain metastases

S Ricciardi, F de Marinis - Current Opinion in Oncology, 2010 - journals.lww.com
Multimodality management of non-small cell lung cancer patie... : Current Opinion in
Oncology Multimodality management of non-small cell lung cancer patients with brain …

Chemotherapy and EGFR tyrosine kinase inhibitors for treatment of brain metastases from non-small-cell lung cancer: survival analysis in 210 patients

Y Fan, Z Huang, L Fang, L Miu, N Lin… - OncoTargets and …, 2013 - Taylor & Francis
Background Chemotherapy and epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors are controversial in the treatment of patients with brain metastases from non-small …

Systemic Treatment Options for Brain Metastases from Non-Small-Cell Lung Cancer.

A Bulbul, PM Forde, A Murtuza… - Oncology …, 2018 - search.ebscohost.com
Brain metastases are common in patients with non-small-cell lung cancer (NSCLC).
Because of associated poor prognosis and limited specific treatment options, there is a real …