The pathogenesis of multiple sclerosis is characterized by a cascade of pathobiologic
events, ranging from focal lymphocytic infiltration and microglia activation to demyelination …

Multiple Sclerosis (MS) is a chronic neurological disease that represents a leading cause of
disability in young adults and is characterized by inflammation and degeneration of both …

Gadolinium enhanced magnetic resonance imaging detects focal blood-brain barrier
breakdown in new inflammatory multiple sclerosis lesions, but such lesions do not correlate …

BACKGROUND AND PURPOSE: Gadolinium SWI is MR imaging that has recently been
reported to be effective in the evaluation of several neurologic disorders, including …

Importance Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous
system traditionally characterized by an initial relapsing-remitting clinical course and focal …

Objective: To determine the frequency and nature of leptomeningeal contrast enhancement
in multiple sclerosis (MS) via in vivo 3-tesla postcontrast T2-weighted, fluid-attenuated …

Gadolinium (Gd)-enhanced MR imaging has greatly improved the understanding of the
pathophysiology of multiple sclerosis (MS) and has provided robust outcome measures for …

Tumefactive demyelinating lesions (TDLs) can mimic brain tumors on radiological images.
TDLs are often referred to as tumefactive multiple sclerosis (TMS), but the heterogeneous …

Magnetic resonance imaging (MRI) is the most sensitive technique for detecting
inflammatory demyelinating lesions in multiple sclerosis (MS) and plays a crucial role in …

Blood-brain barrier (BBB) disruption is probably the first event in the lesion development in
multiple sclerosis (MS). This stage can be visualized by gadolinium-enhanced magnetic …