Assessing abnormal iron content in the deep gray matter of patients with multiple sclerosis versus healthy controls

CA Habib, M Liu, N Bawany… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: It is well known that patients with MS tend to have
abnormal iron deposition in and around the MS plaques, in the basal ganglia and the THA …

Serum iron concentration is associated with subcortical deep gray matter iron levels in multiple sclerosis patients

N Bergsland, S Agostini, MM Laganà, R Mancuso… - …, 2017 - journals.lww.com
Iron deposition has been noted widely in the subcortical deep gray matter (SDGM) of
multiple sclerosis (MS) patients. Recent evidence suggests that serum iron may cross the …

Decreasing brain iron in multiple sclerosis: The difference between concentration and content in iron MRI

F Schweser, J Hagemeier, MG Dwyer… - Human brain …, 2021 - Wiley Online Library
Increased brain iron concentration is often reported concurrently with disease development
in multiple sclerosis (MS) and other neurodegenerative diseases. However, it is unclear …

Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging

EM Haacke, M Makki, Y Ge… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To investigate whether the variable forms of putative iron deposition seen with
susceptibility weighted imaging (SWI) will lead to a set of multiple sclerosis (MS) lesion …

Quantitative assessment of iron accumulation in the deep gray matter of multiple sclerosis by magnetic field correlation imaging

Y Ge, JH Jensen, H Lu, JA Helpern… - American Journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Deposition of iron has been recognized recently as an
important factor of pathophysiologic change including neurodegenerative processes in …

Iron deposition in the precentral grey matter in patients with multiple sclerosis: a quantitative study using susceptibility-weighted imaging

R Rumzan, J Wang, C Zeng, X Chen, Y Li, T Luo… - European Journal of …, 2013 - Elsevier
PURPOSE: Several studies suggest that iron deposition may play a role in multiple sclerosis
(MS) pathology. Three-dimensional (3D) enhanced T2*-weighted angiography (ESWAN) at …

Iron and volume in the deep gray matter: association with cognitive impairment in multiple sclerosis

CM Modica, R Zivadinov, MG Dwyer… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: There is a well-established correlation between deep gray
matter atrophy and cognitive dysfunction in MS. However, the cause of these signs of …

Iron deposition in the gray matter in patients with relapse-remitting multiple sclerosis: a longitudinal study using three-dimensional (3D)-enhanced T2*-weighted …

S Du, SK Sah, C Zeng, J Wang, Y Liu, H Xiong… - European journal of …, 2015 - Elsevier
Purpose To investigate the relationship between the iron content by magnetic resonance
imaging (MRI) and clinic correlation in patients with relapse-remitting multiple sclerosis …

Longitudinal MR imaging of iron in multiple sclerosis: an imaging marker of disease

AJ Walsh, G Blevins, RM Lebel, P Seres, DJ Emery… - Radiology, 2014 - pubs.rsna.org
Purpose To investigate the relationship between magnetic resonance (MR) imaging markers
of iron content and disease severity in patients with multiple sclerosis (MS) over a 2-year …

Multiple sclerosis: validation of MR imaging for quantification and detection of iron

AJ Walsh, RM Lebel, A Eissa, G Blevins, I Catz, JQ Lu… - Radiology, 2013 - pubs.rsna.org
Purpose To investigate the relationship between iron staining and magnetic resonance (MR)
imaging measurements in postmortem subjects with multiple sclerosis (MS). Materials and …