Smart MR imaging agents relevant to potential neurologic applications

CS Bonnet, É Tóth - American journal of neuroradiology, 2010 - Am Soc Neuroradiology
Molecular imaging is aimed at the noninvasive visualization of the expression and function
of bioactive molecules that often represent specific molecular signatures in disease …

Smart contrast agents for magnetic resonance imaging

CS Bonnet, É Tóth - Chimia, 2016 - chimia.ch
By visualizing bioactive molecules or biological parameters in vivo, molecular imaging is
searching for information at the molecular level in living organisms. In addition to …

Detection of enzymatic activity by PARACEST MRI: a general approach to target a large variety of enzymes

T Chauvin, P Durand, M Bernier… - Angewandte Chemie …, 2008 - Wiley Online Library
The search for physiologically responsive diagnostic probes is an important driving force in
the current development of contrast agents for magnetic resonance imaging (MRI) …

Molecular magnetic resonance imaging probes based on Ln3+ complexes

CS Bonnet, E Toth - Advances in Inorganic Chemistry, 2016 - Elsevier
For almost three decades, the application of Gd 3+ complexes as contrast-enhancing agents
has largely contributed to the successful use of magnetic resonance imaging (MRI) both in …

Responsive probes

CS Bonnet, L Tei, M Botta, É Tóth - The Chemistry of Contrast …, 2013 - Wiley Online Library
This chapter presents a large number of responsive Gd3+‐based or paramagnetic chemical
exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) probes with …

Metal complexes as MRI contrast enhancement agents

É Tóth, L Helm, A Merbach - Reference Module in Chemistry …, 2015 - infoscience.epfl.ch
Magnetic resonance imaging is one of the most efficient diagnostic modalities in clinical
radiology and biomedical research. To enhance image contrast, paramagnetic complexes …

Amplification strategies in MR imaging: activation and accumulation of sensing contrast agents (SCAs)

M Querol, A Bogdanov Jr - … Imaging: An Official Journal of the …, 2006 - Wiley Online Library
We review new strategies for the development of Gd3+‐based T1‐relaxation agents and
paramagnetic chemical exchange saturation transfer (PARACEST)“sensing” contrast agents …

[HTML][HTML] Smart MRI agents for detecting extracellular events in vivo: Progress and challenges

D Parrott, WS Fernando, AF Martins - Inorganics, 2019 - mdpi.com
Many elegant inorganic designs have been developed to aid medical imaging. We know
better now how to improve imaging due to the enormous efforts made by scientists in probe …

[HTML][HTML] Targeted contrast agents for molecular MRI

S Lacerda - Inorganics, 2018 - mdpi.com
Molecular magnetic resonance imaging (MRI) provides information non-invasively at cellular
and molecular levels, for both early diagnosis and monitoring therapeutic follow-up. This …

Responsive MRI Agents for Sensing Metabolism in Vivo

LM De Leon-Rodriguez, AJM Lubag… - Accounts of chemical …, 2009 - ACS Publications
Magnetic resonance imaging (MRI) has inherent advantages in safety, three-dimensional
output, and clinical relevance when compared with optical and radiotracer imaging methods …