Intrathecal use of gadobutrol for glymphatic MR imaging: prospective safety study of 100 patients
CS Edeklev, M Halvorsen, G Løvland… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Intrathecal contrast-enhanced glymphatic MR imaging has
shown promise in assessing glymphatic function in patients with dementia. The purpose of …
shown promise in assessing glymphatic function in patients with dementia. The purpose of …
[HTML][HTML] Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols
M Halvorsen, CS Edeklev, J Fraser-Green, G Løvland… - Neuroradiology, 2021 - Springer
Purpose Magnetic resonance imaging (MRI) contrast agents have been used off-label for
diagnosis of cerebrospinal fluid (CSF) leaks and lately also for assessment of the glymphatic …
diagnosis of cerebrospinal fluid (CSF) leaks and lately also for assessment of the glymphatic …
Prospective safety study of intrathecal gadobutrol in different doses
A Sperre, I Karsrud, AHS Rodum… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In our clinical practice, we increasingly use intrathecal
contrast-enhanced glymphatic MR imaging to assess CSF disturbances. However, because …
contrast-enhanced glymphatic MR imaging to assess CSF disturbances. However, because …
Intrathecal injection of gadobutrol: a tale of caution
C Reeves, E Galang, R Padalia, N Tran… - Journal of Pain & …, 2017 - Taylor & Francis
In the field of interventional pain medicine a radiocontrast agent is commonly used in
conjunction with fluoroscopy. Limited work has been published regarding the use of …
conjunction with fluoroscopy. Limited work has been published regarding the use of …
Glymphatic pathway of gadolinium-based contrast agents through the brain: overlooked and misinterpreted
K Deike-Hofmann, J Reuter, R Haase… - Investigative …, 2019 - journals.lww.com
Background The “glymphatic system”(GS), a brain-wide network of cerebrospinal fluid
microcirculation, supplies a pathway through and out of the central nervous system (CNS); …
microcirculation, supplies a pathway through and out of the central nervous system (CNS); …
[HTML][HTML] Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol
G Ringstad, LM Valnes, SAS Vatnehol, AH Pripp… - Neuroradiology, 2023 - Springer
Purpose A possible pathway behind gadolinium retention in brain is leakage of contrast
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …
MRI with intrathecal MRI gadolinium contrast medium administration: a possible method to assess glymphatic function in human brain
PK Eide, G Ringstad - Acta radiologica open, 2015 - journals.sagepub.com
Recently, the “glymphatic system” of the brain has been discovered in rodents, which is a
paravascular, transparenchymal route for clearance of excess brain metabolites and …
paravascular, transparenchymal route for clearance of excess brain metabolites and …
Quantification approaches for magnetic resonance imaging following intravenous gadolinium injection: A window into brain‐wide glymphatic function
SB Richmond, S Rane, MR Hanson… - European Journal of …, 2023 - Wiley Online Library
The glymphatic system is a brain‐wide network of perivascular pathways along which
cerebrospinal fluid and interstitial fluid rapidly exchange, facilitating solute and waste …
cerebrospinal fluid and interstitial fluid rapidly exchange, facilitating solute and waste …
Measuring glymphatic flow in man using quantitative contrast-enhanced MRI
On the basis of animal models, glymphatic flow disruption is hypothesized to be a factor in
the development of Alzheimer's disease. We report the first quantitative study of glymphatic …
the development of Alzheimer's disease. We report the first quantitative study of glymphatic …
Pre-clinical evaluation of gadobutrol: a new, neutral, extracellular contrast agent for magnetic resonance imaging
H Vogler, J Platzek, G Schuhmann-Giampieri… - European journal of …, 1995 - Elsevier
The Gd3+-complex of 10-(2, 3-dihydroxy-l-hydroxymethylpropyl)-1, 4, 7, 10-
tetraazacyclododecane-1, 4, 7-triacetic acid (gadobutrol) is a new, neutral Gd-chelate for …
tetraazacyclododecane-1, 4, 7-triacetic acid (gadobutrol) is a new, neutral Gd-chelate for …