BACKGROUND AND PURPOSE: Multiple case series of vertebroplasty outcomes have
been published, though no large, placebo controlled trial has yet been performed. Our aim …

Purpose To evaluate 1-year outcomes of the Investigational Vertebroplasty Safety and
Efficacy Trial (INVEST), a blinded, randomized, controlled trial to investigate the …

BACKGROUND AND PURPOSE: Vertebroplasty is rapidly disseminating as a treatment for
vertebral compression fractures, but its efficacy has not been assessed with a well-validated …

BACKGROUND AND PURPOSE: Percutaneous polymethylmethacrylate (PMMA)
vertebroplasty has become a common procedure for treatment of pain and disability …

BACKGROUND AND PURPOSE: Our aim was to determine whether referral patterns and
rates of vertebroplasties at the Mayo Clinic have changed after the publication of the INVEST …

Background The treatment of painful osteoporotic vertebral compression fractures has
historically been limited to several weeks of bed rest, anti-inflammatory and analgesic …

Vertebroplasty is a cost-effective procedure for the relief of pain in appropriately selected
patients when performed by a skilled practitioner. The currently accepted indications and …

In contrast to previous studies that have used less rigorous designs, our trials provided
independent, valid, and unbiased estimates of the efficacy of vertebroplasty; the negative …

Vertebroplasty: when randomized placebo-controlled trial results clash with common belief -
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The learning objectives for this article include improved understanding of the strength of
existing literature to support the practice of vertebroplasty, providing an update on current …