BACKGROUND AND PURPOSE: Susceptibility MR imaging contrast variations reflect
alterations in brain iron and myelin content, making this imaging tool relevant to studies of …

BACKGROUND AND PURPOSE: Magnetic susceptibility measured with quantitative
susceptibility mapping has been proposed as a biomarker for demyelination and …

Purpose Recent magnetic resonance imaging (MRI) studies have revealed heterogeneous
magnetic susceptibility contrasts in multiple sclerosis (MS) lesions. Due to its sensitivity to …

Purpose To elucidate the mechanism of magnetic resonance (MR) imaging contrast in
multiple sclerosis (MS) lesion appearance by using susceptibility-weighted imaging and to …

BACKGROUND AND PURPOSE: MR imaging studies have demonstrated that magnetic
susceptibility in multiple sclerosis lesions is dependent on lesion age. The objective of this …

Background Susceptibility MRI techniques, such as phase and quantitative susceptibility
mapping (QSM) reveal lesion heterogeneity in MS, including the presence of lesions with …

Purpose To evaluate the potential of quantitative susceptibility (QS) and R2* mapping as
surrogate biomarkers of clinically relevant, age-adjusted demyelination and iron deposition …

Susceptibility‐sensitive magnetic resonance imaging (MRI) has gained importance in
multiple sclerosis (MS) research because of its versatility, high resolution and excellent …

BACKGROUND AND PURPOSE: Quantitative susceptibility mapping and R2* are sensitive
to myelin and iron changes in multiple sclerosis lesions. This study was designed to …

BACKGROUND AND PURPOSE: Modifications of magnetic susceptibility have been
consistently demonstrated in the subcortical gray matter of MS patients, but some …