PURPOSE To improve the prediction of individual survival in patients with intracranial
astrocytomas through the analysis of volumetric tumor doubling time (VDt) and DNA ploidy …

✓ High-grade astrocytic tumors constitute the most serious as well as the most common
group of primary brain tumors. Although several prognostic factors have been proposed …

✓ The S-phase fraction and the DNA ploidy type in 134 astrocytomas (18 Grade II, 46 Grade
III, and 70 Grade IV astrocytomas) were studied using flow cytometry in a retrospective study …

✓ The histological grade and the bromodeoxyuridine (BUdR) labeling index of 60
astrocytomas of “ordinary” cell types (fibrillary, protoplasmic, gemistocytic, and anaplastic …

In adult cerebral astrocytomas, the more anaplasia that is present, the more malignancy that
occurs. Cell proliferation antigen staining (MIB-1) and DNA labeling methods for apoptosis …

Surgical specimens from 165 adults with cerebral astrocytoma were reviewed to establish
the prognostic value of histologic factors when studied both individually and in combination …

Abstract FLOW CYTOMETRY WAS used to determine the deoxyribonucleic acid ploidy and
proliferative activity of 230 astrocytomas. The relationships among survival, ploidy …

Despite their histological similarity, low-grade astrocytomas vary widely in their clinical
behavior. To elucidate this variable behavior, we measured the proliferative potential of 69 …

The prognostic value of histologic or cytologic features were examined in 317 patients with
an astrocytic glioma. Of 46 features examined 7 morphologic characteristics of nucleus and …

✓ In order to examine the correlation between prognosis and the histological features of
nuclear atypia, mitosis, endothelial proliferation, and necrosis in supratentorial adult …