Comment on “Global N-Acetylaspartate Declines Even in Benign Multiple Sclerosis”
F Aboul-Enein - American Journal of Neuroradiology, 2011 - Am Soc Neuroradiology
We have read with great interest the article “Global N-Acetylaspartate Declines Even in
Benign Multiple Sclerosis” by Rigotti et al. 1 It is generally accepted that axonal injury is the …
Benign Multiple Sclerosis” by Rigotti et al. 1 It is generally accepted that axonal injury is the …
Global N-acetylaspartate concentration in benign and non-benign multiple sclerosis patients of long disease duration
L Achtnichts, O Gonen, DJ Rigotti, JS Babb… - European journal of …, 2013 - Elsevier
Background and objective To examine whether clinically benign multiple sclerosis patients
(BMS) show similar losses of their global N-acetylaspartate (NAA) neuronal marker relative …
(BMS) show similar losses of their global N-acetylaspartate (NAA) neuronal marker relative …
Global N-acetylaspartate declines even in benign multiple sclerosis
DJ Rigotti, O Gonen, RI Grossman… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Neuro-axonal damage is a well known sequelae of MS
pathogeneses. Consequently, our aim was to test whether the∼ 20% of patients with MS …
pathogeneses. Consequently, our aim was to test whether the∼ 20% of patients with MS …
N-Acetyl-L-Aspartate in Multiple Sclerosis
GA Criste, BD Trapp - N-Acetylaspartate: A Unique Neuronal Molecule in …, 2006 - Springer
4. Conclusion It is well established that axonal pathology is the basis of permanent disability
in MS from its earliest stage. The promise of NAA measurement is that, it provides a specific …
in MS from its earliest stage. The promise of NAA measurement is that, it provides a specific …
[CITATION][C] N‐acetylaspartate: Usefulness as an indicator of viable neuronal tissue
Martin and colleagues1 reported a case study of a child with “developmental delay,” studied
with proton magnetic resonance spectroscopy (MRS). According to the authors, shortecho …
with proton magnetic resonance spectroscopy (MRS). According to the authors, shortecho …
[PDF][PDF] N-acetylaspartate—a marker of neuronal integrity
EV Sullivan, E Adalsteinsson, DM Spielman… - Annals of …, 2001 - researchgate.net
Martin and colleagues1 reported a case study of a child with “developmental delay,” studied
with proton magnetic resonance spectroscopy (MRS). According to the authors, shortecho …
with proton magnetic resonance spectroscopy (MRS). According to the authors, shortecho …
Reproducibility of three whole-brain N-acetylaspartate decline cohorts in relapsing-remitting multiple sclerosis
BACKGROUND AND PURPOSE: The cross-sectional rate of whole-brain N-acetylaspartate
(NAA, a neuronal cell marker) loss in clinically similar relapsing-remitting multiple sclerosis …
(NAA, a neuronal cell marker) loss in clinically similar relapsing-remitting multiple sclerosis …
Neurological disability correlates with spinal cord axonal loss and reduced N‐acetyl aspartate in chronic multiple sclerosis patients
Axonal degeneration has been proposed as a cause of irreversible neurological disability in
multiple sclerosis (MS) patients. The purpose of this study was to quantify axonal loss in …
multiple sclerosis (MS) patients. The purpose of this study was to quantify axonal loss in …
Axonal dysfunction and disability in a relapse of multiple sclerosis: longitudinal study of a patient
In a 6-year longitudinal study of a patient with relapsing progressive multiple sclerosis (MS),
we used proton magnetic resonance spectroscopy to asses N-acetylaspartate (NAA) from a …
we used proton magnetic resonance spectroscopy to asses N-acetylaspartate (NAA) from a …
Total brain N-acetylaspartate: A new measure of disease load in MS
Objective: To quantitate the extent of neuronal cell loss in MS via the whole brain's N-
acetylaspartate (NAA) concentration (WBNAA). Methods: Because NAA is assumed to be …
acetylaspartate (NAA) concentration (WBNAA). Methods: Because NAA is assumed to be …