Application of deep learning to predict standardized uptake value ratio and amyloid status on 18F-florbetapir PET using ADNI data

F Reith, ME Koran, G Davidzon… - American Journal of …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cortical amyloid quantification on PET by using the
standardized uptake value ratio is valuable for research studies and clinical trials in …

Amyloid PET quantification via end-to-end training of a deep learning

JY Kim, HY Suh, HG Ryoo, D Oh, H Choi… - Nuclear medicine and …, 2019 - Springer
Purpose Although quantification of amyloid positron emission tomography (PET) is important
for evaluating patients with cognitive impairment, its routine clinical use is hampered by …

[HTML][HTML] DeepAD: A deep learning application for predicting amyloid standardized uptake value ratio through PET for Alzheimer's prognosis

S Maddury, K Desai - Frontiers in Artificial Intelligence, 2023 - frontiersin.org
Amyloid deposition is a vital biomarker in the process of Alzheimer's diagnosis. 18F-
florbetapir PET scans can provide valuable imaging data to determine cortical amyloid …

[HTML][HTML] Improved amyloid burden quantification with nonspecific estimates using deep learning

H Liu, YH Nai, F Saridin, T Tanaka, J O'Doherty… - European Journal of …, 2021 - Springer
Purpose Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from
amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding …

Visual interpretation of [18F]Florbetaben PET supported by deep learning–based estimation of amyloid burden

JY Kim, D Oh, K Sung, H Choi, JC Paeng… - European Journal of …, 2021 - Springer
Purpose Amyloid PET which has been widely used for noninvasive assessment of cortical
amyloid burden is visually interpreted in the clinical setting. As a fast and easy-to-use visual …

Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning

KT Chen, M Schürer, J Ouyang, MEI Koran… - European journal of …, 2020 - Springer
Purpose We aimed to evaluate the performance of deep learning-based generalization of
ultra-low-count amyloid PET/MRI enhancement when applied to studies acquired with …

[HTML][HTML] Staging and quantification of florbetaben PET images using machine learning: impact of predicted regional cortical tracer uptake and amyloid stage on clinical …

JP Kim, J Kim, Y Kim, SH Moon, YH Park, S Yoo… - European Journal of …, 2020 - Springer
Purpose We developed a machine learning–based classifier for in vivo amyloid positron
emission tomography (PET) staging, quantified cortical uptake of the PET tracer by using a …

Fast and accurate amyloid brain PET quantification without MRI using deep neural networks

SK Kang, D Kim, SA Shin, YK Kim… - Journal of Nuclear …, 2023 - Soc Nuclear Med
This paper proposes a novel method for automatic quantification of amyloid PET using deep
learning–based spatial normalization (SN) of PET images, which does not require MRI or CT …

Deep residual inception encoder‐decoder network for amyloid PET harmonization

J Shah, F Gao, B Li, V Ghisays, J Luo… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Multiple positron emission tomography (PET) tracers are available for amyloid
imaging, posing a significant challenge to consensus interpretation and quantitative …

Predicting future amyloid biomarkers in dementia patients with machine learning to improve clinical trial patient selection

FH Reith, EC Mormino… - Alzheimer's & Dementia …, 2021 - Wiley Online Library
Abstract Introduction In Alzheimer's disease, asymptomatic patients may have amyloid
deposition, but predicting their progression rate remains a substantial challenge with …