Subacute MTX-induced encephalopathy is characterized by an abrupt onset of focal
neurologic deficits within days after intrathecal or systemic therapy. Demyelination is one …

Methotrexate (MTX) is a major cause of treatment-related acute neurotoxicity. We report on
clinical and imaging findings of reversibly restricted diffusion in a patient with transient …

Methotrexate (MTX) is an indispensable antimetabolite for the treatment of oncological and
immunological disorders in all age groups. Chronic leukoencephalopathy is a well know …

Methotrexate (MTX) is an indispensable antimetabolite for the treatment of oncological and
immunological disorders in all age groups. It can be administrated intravenously as well as …

We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness
and aphasia. Diagnostic imaging showed restricted diffusion and fluid-attenuated inversion …

Methotrexate (MTX) has poor central nervous system penetration as an oral agent. Although
commonly seen with intrathecal dosing, there are only few reports of oral MTXJinduced …

Diffusion‐weighted imaging characteristics of methotrexate‐induced acute encephalopathy -
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We describe longitudinal diffusion-weighted MRI findings of sub-acute leukoencephalopathy
following methotrexate therapy in a 24-year-old man diagnosed with pre-B-cell acute …

Stroke mimics are often encountered in emergency departments, and previous studies have
demonstrated that 25.3% of patients diagnosed with acute ischemic stroke are actually …

Methotrexate (MTX) is a widely used chemotherapeutic agent that can cause acute,
subacute, and chronic neurological complications. Subacute MTX neurotoxicity is manifest …