BACKGROUND AND PURPOSE: Often diagnosed at birth or in early childhood,
mitochondrial disease presents with a variety of clinical symptoms, particularly in organs and …

Recent advances in diffusion tensor imaging (DTI) have made it possible to reveal white
matter anatomy and to detect neurological abnormalities in children. However, the clinical …

Diffusion tensor imaging (DTI) represents a promising tool for the early diagnosis of certain
brain diseases. Many DTI studies have compared differences in local diffusivity in specific …

BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) can noninvasively detect in
vivo white matter (WM) abnormalities on the basis of anisotropic diffusion properties. We …

Diffusion tensor imaging (DTI) is a relatively new addition to routine MR imaging. DTI
exploits the preferential movement of water protons within the brain along the axis of the …

BACKGROUND AND PURPOSE: Loss of integrity in nonlesional white matter occurs as a
fundamental feature of multiple sclerosis in adults. The purpose of our study was to evaluate …

Objective: Fractional anisotropy (FA) is a powerful measure to study the integrity of the
cerebral white matter in vivo. However, because clinical FA assessments are frequently …

The authors have reviewed the diffusion tensor imaging (DTI) of the brain stem in 19
subjects, consisting of 15 normal volunteers and four multi-system atrophy patients. The …

BACKGROUND AND PURPOSE: Brain white matter is frequently affected in mitochondrial
diseases; optic atrophy gene 1-autosomal dominant optic atrophy and Leber hereditary optic …

Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and
quantitative information about the micro-architecture of white matter. DTI and its post …