Quantitative measurement of microvascular permeability in human brain tumors achieved using dynamic contrast-enhanced MR imaging: correlation with histologic …

HC Roberts, TPL Roberts… - American Journal of …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Dynamic contrast-enhanced MR imaging may be used to
quantify tissue fractional blood volume (fBV) and microvascular permeability. We tested this …

Correlation of microvascular permeability derived from dynamic contrast-enhanced MR imaging with histologic grade and tumor labeling index: a study in human brain …

HC Roberts, TPL Roberts, AW Bollen, S Ley… - Academic radiology, 2001 - Elsevier
RATIONALE AND OBJECTIVES: Dynamic contrast material–enhanced magnetic resonance
(MR) imaging may be used to quantify fractional blood volume (fBV) and microvascular …

Quantitative measurement of leakage volume and permeability in gliomas, meningiomas and brain metastases with dynamic contrast-enhanced MRI

L Lüdemann, W Grieger, R Wurm, P Wust… - Magnetic resonance …, 2005 - Elsevier
The spatial properties and function of the tumor vasculature differ with the tumor type and
grade. T1-weighted dynamic contrast-enhanced imaging technique enables the …

Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade

M Law, S Yang, JS Babb, EA Knopp… - American Journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) and vascular
permeability (Ktrans) permit in vivo assessment of glioma microvasculature. We assessed …

Quantification of endothelial permeability, leakage space, and blood volume in brain tumors using combined T1 and T2* contrast‐enhanced dynamic MR imaging

XP Zhu, KL Li, ID Kamaly‐Asl… - Journal of Magnetic …, 2000 - Wiley Online Library
This study describes a method for imaging brain tumors that combines T1‐weighted (T1W)
and T2*‐weighted (T2* W) dynamic contrast‐enhanced acquisitions. Several technical …

Dynamic, contrast-enhanced CT of human brain tumors: quantitative assessment of blood volume, blood flow, and microvascular permeability: report of two cases

HC Roberts, TPL Roberts, TY Lee… - American journal of …, 2002 - Am Soc Neuroradiology
We present two patients with metastatic brain tumors who underwent dynamic contrast-
enhanced CT that yielded estimates of blood volume, blood flow, and microvascular …

Evaluation of microvascular permeability with dynamic contrast-enhanced MRI for the differentiation of primary CNS lymphoma and glioblastoma: radiologic …

P Kickingereder, F Sahm, B Wiestler… - American journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Dynamic contrast-enhanced MR imaging can provide in
vivo assessment of the microvasculature in intracranial tumors. The aim of the present study …

Magnetic resonance perfusion and permeability imaging in brain tumors

S Lacerda, M Law - Neuroimaging Clinics, 2009 - neuroimaging.theclinics.com
The effects of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF)
and other growth factors on vascular perfusion and permeability have been under …

Comparison of permeability in high-grade and low-grade brain tumors using dynamic susceptibility contrast MR imaging

JM Provenzale, GR Wang, T Brenner… - American Journal of …, 2002 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to compare permeability measurements in high-
grade and low-grade glial neoplasms using a T2*-weighted method. Our hypothesis was …

Comparison of microvascular permeability measurements, Ktrans, determined with conventional steady-state T1-weighted and first-pass T2*-weighted MR imaging …

S Cha, L Yang, G Johnson, A Lai… - American journal …, 2006 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The widely accepted MR method for quantitating brain
tumor microvascular permeability, Ktrans, is the steady-state T1-weighted gradient-echo …