Imaging Biomarker for Early-Stage Alzheimer Disease: Utility of Hippocampal Histogram Analysis of Diffusion Metrics
H Takahashi, Y Takami, S Takeda… - American Journal …, 2024 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Biomarkers have been required for diagnosing early
Alzheimer disease. We assessed the utility of hippocampal diffusion parameters for …
Alzheimer disease. We assessed the utility of hippocampal diffusion parameters for …
[HTML][HTML] Diffusion tensor studies and voxel-based morphometry of the temporal lobe to determine the cognitive prognosis in cases of Alzheimer's disease and mild …
T Taoka, F Yasuno, M Morikawa, M Inoue, K Kiuchi… - Springerplus, 2016 - Springer
Purpose The purpose of the current study was to assess the feasibility of diffusion tensor
imaging (DTI) parameters for determining the prognosis of Alzheimer's disease (AD). We …
imaging (DTI) parameters for determining the prognosis of Alzheimer's disease (AD). We …
The Role of Diffusion Tensor Imaging in Detecting Microstructural Changes in Prodromal A lzheimer's Disease
B Zhang, Y Xu, B Zhu, K Kantarci - CNS neuroscience & …, 2014 - Wiley Online Library
The MRI technique diffusion tensor imaging (DTI) is reviewed along with microstructural
changes associated with prodromal A lzheimer's disease (AD) as a potential biomarker for …
changes associated with prodromal A lzheimer's disease (AD) as a potential biomarker for …
Diffusion tensor imaging measures of brain connectivity for the early diagnosis of Alzheimer's disease
A Marcos Dolado, C Gomez-Fernandez… - Brain …, 2019 - liebertpub.com
The prognostic capacity of the diffusion tensor imaging measures fractional anisotropy (FA)
and mean diffusivity (MD) to detect mild cognitive impairment (MCI) progression to …
and mean diffusivity (MD) to detect mild cognitive impairment (MCI) progression to …
Diffusion tensor in posterior cingulate gyrus: correlation with cognitive decline in Alzheimer's disease
T Yoshiura, F Mihara, K Ogomori, A Tanaka… - …, 2002 - journals.lww.com
To determine whether the diffusion abnormalities in brains with Alzheimer's disease (AD)
correlate with disease severity, we studied 34 AD patients using diffusion tensor MRI. Mean …
correlate with disease severity, we studied 34 AD patients using diffusion tensor MRI. Mean …
[HTML][HTML] White matter alterations in early-stage Alzheimer's disease: A tract-specific study
Introduction Diffusion magnetic resonance imaging may allow for microscopic
characterization of white matter degeneration in early stages of Alzheimer's disease …
characterization of white matter degeneration in early stages of Alzheimer's disease …
Regional and global changes in cerebral diffusion with normal aging
AO Nusbaum, CY Tang… - American Journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: We used quantitative diffusion MR imaging to investigate
the microstructural changes that occur in white matter during normal aging in order to …
the microstructural changes that occur in white matter during normal aging in order to …
Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease
G Douaud, RAL Menke, A Gass… - Journal of …, 2013 - Soc Neuroscience
Diffusion imaging is a promising marker of microstructural damage in neurodegenerative
disorders, but interpretation of its relationship with underlying neuropathology can be …
disorders, but interpretation of its relationship with underlying neuropathology can be …
Hippocampal mean diffusivity for the diagnosis of dementia and mild cognitive impairment in primary care
K Brueggen, M Dyrba, I Kilimann, J Henf… - Current Alzheimer …, 2018 - ingentaconnect.com
Background: Hippocampal mean diffusivity (MD) measured by Diffusion-Tensor Imaging is a
promising diagnostic marker for Mild Cognitive Impairment (MCI) and dementia. Its …
promising diagnostic marker for Mild Cognitive Impairment (MCI) and dementia. Its …
[HTML][HTML] Selective changes in white matter integrity in MCI and older adults with cognitive complaints
Y Wang, JD West, LA Flashman, HA Wishart… - … et Biophysica Acta (BBA …, 2012 - Elsevier
BACKGROUND: White matter changes measured using diffusion tensor imaging have been
reported in Alzheimer's disease and amnestic mild cognitive impairment, but changes in …
reported in Alzheimer's disease and amnestic mild cognitive impairment, but changes in …
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